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Oral versus Intravenous Opioid Dosing for the Initial ...
IV oxycodone and morphine were used by patients with a patient-controlled analgesia pump, suggesting that the two drugs are equipotent in this type of pain when given intravenously.12 Oral oxycodone has a bioavail-ability of 60% to 87% in cancer patients.13–16 Therefore, using a bioavailability quotient of 0.8, we estimated that

[PDF File]Onset, Peak, and Duration of Common Pain Medications Table
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Oral Sedation, nausea/vomiting, constipation, respiratory depression, delirium, pruritis, life-Threatening QT Prolongation, monitor patients closely for respiratory depression, especially within the first 24 to 72 hours, narrow therapeutic index (dose carefully) Morphine, immediate release 15 -60 1 3 -6 Oral

[PDF File]090714 opioid conversions
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oral morphine Example conversions (These apply to single doses or total daily dose) Morphine (oral) 1 30mg 1. To convert 60 mg of Morphine (sc) 2 to 1 15mg oral Morphine to Morphine (iv) 3 to 1 10mg subcutaneous Morphine Diamorphine (sc) 3 to 1 10mg divide by 2 to give 30 mg. Oxycodone (oral…

Transdermal and Parenteral Fentanyl Dosage Calculations ...
at least 60 mg of oral morphine, 30 mg of oral oxycodone, or at least 8 mg of oral hydromorphone or an equianalgesic dose of another opioid. Fentanyl patch use in non-opioid tolerant patients has resulted in fatal respiratory depression. n Consult the prescribing information to determine the …

[PDF File]OPIOID ADMINISTRATION GUIDELINES
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mg/day of IV morphine Convert to oral morphine: 21.6 x 3 = 64.8 mg or oral morphine per day. Round this down to 60 mg per day and divide by 6 to determine 4 hourly dose (10 mg PO Q4H). If the pain model is decreasing (ie post-surgical) the dose may be decreased by 30% (eg 6 mg PO Q4H)

[PDF File]GOLDEN RULE: WHEN CHANGING FROM ONE OPIOID TO …
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αNational and international guidelines also support the use of a 2:1 ratio when switching between morphine and oxycodone. Oxycodone is available as immediate release capsules 5mg, 10mg and 20mg, liquid 1mg/ml or 10mg/ml and sustained release tablets 5mg, 10mg, 20mg, 40mg and 80mg.

[PDF File]Opioid conversion guide - Department of Health
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30 mg morphine/day ÷ conversion factor = oxycodone/day . 30 mg ÷ 1.5 = 20 mg oxycodone/day . Equianalgesic doses of oral opioids . If a patient is taking Panadeine Forte ® 2 tablets qid . that is, (2 x 30 mg codeine) x 4 doses or 240 mg codeine/day ... 30 mg oral morphine x 2 doses/day or 60 mg oral morphine/day Then,

[PDF File]Rational Use of Sublingual Opioids in Palliative Medicine
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sublingual, oral, and intramuscular morphine sulfate in patients with cancer pain (n 6). Sub-lingual retention time was not specified, nor was the fate of the morphine-rich saliva. Blood sam-ples were drawn periodically and serum assayed by RIA. Bioavailabilities of sublingual and oral morphine were 23% and 25%, respectively, a non-

[PDF File]PEDIATRIC DOSING GUIDELINES - ANALGESICS / SEDATIVES ...
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Oxycodone 0.05 - 0.2 mg/kg/dose Q4-6 (Liquid: 1 mg/ml oxycodone) (Percocet tab: 5 mg oxycodone/325 mg acetaminophen; Percocet liquid: 1 mg oxycodone/65 mg acetaminophen/mL) **Special Liquid Formulation, please allow 24 hours for preparation UNC Health Care Central Outpatient Pharmacy: (984) 974-2374

[PDF File]Clinical Guideline Pain Management
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Max 4g daily. Or use IV paracetamol (for dosing see under mild pain) + Morphine sulphate oral solution 10mg/5mL 5 to 10mg every 4 hours when required If oral route not possible: give 2.5 to 5mg of morphine sulphate injection intramuscularly (IM) every 4 hours or 2.5mg IV hourly when required. (And STOP any weak opioids — eg, codeine or tramadol).

Iv morphine to oral oxycodone