Lipoprotein metabolism

    • [PDF File]Chapter 1 Basics in Lipoprotein Metabolism - Springer

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      These are “conductor” lipoproteins that can orchestrate the efficiency of lipoprotein metabolism. These two lipoprotein classes are being constantly exchanged between HDL and VLDL/LDL particles after meals [5]. Their capacity to move between particles regulates the rate of fatty acid, cholesterol and phospholipid turnover [6].


    • An Overview of Lipoprotein Metabolism - Springer

      ulating lipoprotein metabolism, we should not ignore entirely the significance of their lipid components, which do exert some influence on their processing by affecting both their size and the composition of their hydrophobic core. For example, the triglyceride buried within a lipoprotein makes it subject to the action of tissue


    • Lipoprotein Metabolism - American Journal of Kidney Diseases

      Lipoprotein lipase is a hydrolytic enzyme that is present primarily on endothelial cells in the capillary beds of a number of tissues, including muscle, adipose tissue, and breast tissue. 15 The enzyme is normally present in plasma in very low concentrations, but may be released by the injection of heparin.


    • Lipoprotein lipase and lipolysis: central roles in ...

      lipoprotein metabolism and atherogenesis Ira J. Goldberg Department of Medicine, Columbia University College of Physicians and Surgeons, 630 West 168th Street, New York, NY 10032 Abstract Although it has been known for over 50 years that lipoprotein lipase (LPL) hydrolyzes triglyceride in chylomi-


    • Plasma lipoproteins: apolipoprotein structure and function.

      Abaract Plasma lipoprotein metabolism is regulated and controlled by the specific apolipoprotein (apo-) constituents of the various lipoprotein classes. The major apolipoproteins include apoE, apoB, apoA-I, apoA-11, apoA-IV, apoC-I, apoC- 11, and apoC-Ill. Specific apolipoproteins function in the


    • Human Plasma Lipoproteins: Biochemical and Clinical Aspects

      Fig. 3 Scheme ofthe metabolism ofhuman plasma lipoproteins in the vascular space with particular focus on the function ofthe liver. role in biosynthesis of plasma lipoproteins and sub­ serves a central role in lipoprotein metabolism. The liver secretes two types ofnascent lipoproteins, one is a nascent VLDL, rich in triglycerides and apo B


    • [PDF File]CHAPTER 2 Lipoprotein Metabolism - Springer

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      in lipid-lipoprotein metabolism. Of particular importance is apoC-II, the activator of lipoprotein lipase, which is responsible for the perivascular hydrolysis of triglycerides contained in lipoproteins to monoglycerides and free fatty acids (LARoSA et al. 1970; HAVEL et al. 1970; JACKSON et al. 1977; HOSPATTANKAR et al. 1984).


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