Liver and cholesterol metabolism
[DOC File]Chapter 7 – Metabolism
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In liver mitochondria : as a substrate in ketone bodies metabolism. HMG-CoA undergoes oxidation reaction in liver mitochondria to form acetone and . 3-hydroxybutyrate. The enzymes used are HMG-CoA synthase and HMG-CoA lyase. In cytosol : as a substrate in cholesterol metabolism. HMG-CoA is found in cholesterol synthesis.
[DOC File]Caveat: The following synopsis of normal liver physiology ...
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Endogenously synthesized lipids: from liver to other tissues. VLDL metabolism. Formation. Liver. Apo B-100. Hydrolysis by LPL. IDL Uptake. LDL formation. Hepatic lipase. LDL metabolism. Receptor mediated uptake. HMG CoA Reductase. ACAT. Scavenger receptor. Reverse transport of cholesterol from extrahepatic tissues to the liver - HDL metabolism ...
[DOC File]Lipid Metabolism - University of Babylon
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Cholesterol Metabolism. Cholesterol is present in tissues and in plasma either as free cholesterol or as a storage form, combined with along-chain fatty acid as cholesteryl ester. In plasma, both forms are transported in lipoproteins . Functions of Cholesterol. Cholesterol is an amphipathic lipid and as such is an essential structural 1.
Cholesterol Metabolism and the Liver - ScienceDirect
Also a large amount of the cholesterol used by our body is formed in the liver, and the liver is also the major site for production of fats from carbohydrates and proteins. Protein metabolism: The liver's role in protein metabolism is probably the most important of its metabolic functions.
[DOC File]Lipid and Cholesterol Transport
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The liver is the most metabolically active organ in the body. Functions of the. Liver. include: Carbohydrates Converts fructose and galactose to glucose. Makes and stores glycogen. Converts glycogen to glucose. Converts excess glucose to fatty acids Lipids Makes and breaks down triglycerides, phospholipids, and cholesterol
[DOC File]Introduction to Cholesterol Metabolism
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T2 (present in natural dessicated thyroid), lowers LDL cholesterol (Ehrenkranz, 2011) Alsheikh-Ali AA, Maddukuri PV, Han H, Karas RH. Effect of the magnitude of lipid lowering on risk of elevated liver enzymes, rhabdomyolysis, and cancer: insights from large randomized statin trials. J Am Coll Cardiol. 2007 Jul 31;50(5):409-18.
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