Loop diuretics such as furosemide

    • Diuretics - SAGE Journals

      https://journals.sagepub.com/doi/pdf/10.1177/1074248413497257

      In the setting of heart failure, long acting loop diuretics azosemide and torasemide are more effective in improving heart failure outcomes than the far more commonly used short acting furosemide. Evening dosing of diuretics …

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    • [PDF File] VASODILATORY PROSTAGLANDINS AND LOOP …

      https://link.springer.com/content/pdf/10.1007/978-1-4615-3884-4_71.pdf

      Indomethacin, a prostaglandin synthesis inhibitor, diminishes the diuretic effe~t of furosemide. Three studies in patients with congestive heart failure, renal failure or aortic insufficiency have shown that hemodynamics and renal effects of acute and chronically ap­ plied piretanide correlate with an increase in vasodilatory prostaglandins.

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    • The Long and Winding Road: Loop Diuretics in Neonatology

      https://www.jpeds.com/article/S0022-3476(20)31556-0/pdf

      So, despite a paucity of systematic study, the use of furosemide and other diuretics in the neonatal intensive care unit (NICU) became rapidly entrenched in neonatology prac-tice, probablyreinforced byempiric observations of better respi-ratory function manifest by a decrease in oxygen requirements, decreased ventilator settings, and diminished ...

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    • Effect of Torsemide Versus Furosemide on Symptoms and …

      https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.123.064842

      BACKGROUND:99981231160000-08'00' Loop diuretics are a primary therapy for the symptomatic treatment of heart failure (HF), but whether torsemide improves patient symptoms and quality of life better than furosemide remains unknown. As prespecified secondary end points, the TRANSFORM-HF trial (Torsemide Comparison …

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    • Diuretic Treatment in Heart Failure

      https://www.nejm.org/doi/pdf/10.1056/NEJMra1703100

      Loop diuretics have complex effects on renal and systemic hemodynamics, which are influenced by the dose and route of administration, concomitant disease and treatment, and long-term use.

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    • [PDF File] Nephrolithiasis in Children - Stanford Medicine

      https://med.stanford.edu/content/dam/sm/pednephrology/documents/secure/Nephrolithiasis-Children.pdf

      Distal renal tubular acidosis, Bartter syndrome, hypomagnesemia-hypercalciuria, and urinary infections also produce stones and increase calcium excretion. Common iatrogenic causes of hypercalciuria include treatment with loop diuretics (such as furosemide or bumet-anide), prednisone, and adrenocorticotrophic hormone.

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    • Ototoxicity of Loop Diuretics

      https://www.oto.theclinics.com/article/S0030-6665(20)30770-2/pdf

      The most commonly used of the high- ceiling or loop diuretics are furosemide and bumetanide. Ethacrynic acid, the first member of this group of drugs, is occasionally used in cases of allergy or refractoriness to furosemide. A list of loop diuretics is given in Table 1.

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    • Safety of Furosemide in Premature Infants: A Systematic …

      https://cdr.lib.unc.edu/downloads/7h149t38c

      Despite the proposed benefits and biological plausibility of using furosemide to improve respiratory outcomes, the efficacy of furosemide in premature infants has not been established. A Cochrane systematic review examining loop diuretics for preterm infants found no evidence to

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    • [PDF File] Loop Diuretics in Clinical Practice - KoreaMed Synapse

      https://synapse.koreamed.org/upload/SynapseData/PDFData/0158ebp/ebp-13-17.pdf

      In this article, we review five important aspects of loop diuretics, in particular furosemide, which must be considered when prescribing this medi-cine: (1) oral versus intravenous treatment, (2) dosage, (3) continuous versus bolus infusion, (4) application in chronic kidney disease patients, and (5) side effects.

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    • [PDF File] Inpatient Diuretic Management of Acute Heart Failure: A …

      https://link.springer.com/content/pdf/10.1007/s40256-020-00463-5.pdf

      Because they produce potent diuresis and natriuresis, loop diuretics such as furosemide, torsemide, or bumetanide remain a cornerstone in the management of AHF [1]. In the Acute Decompensated Heart Failure Registry (ADHERE), 90% of hospitalized patients with AHF were treated with intravenous loop diuretics [2].

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    • Furosemide and Loop Diuretics in Human Asthma - CHEST

      https://journal.chestnet.org/article/S0012-3692(16)38986-3/pdf

      Furosemide and Loop Diuretics in Human Asthma. (Lockhart, Slutsky) demonstrate an inhibitory effect of furosemide on airway nerves in man. Inhaled furosemide reduces the cough response to nebulized low-chloride, hypo osmolar solutions in normal subjects, and, to a lesser extent, in asthmatic subjects,21-23 but has no effect on both capsaicin ...

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    • How to prescribe loop diuretics in oedema - JSTOR

      https://www.jstor.org/stable/26957626

      Loop diuretics are commonly prescribed to manage oedema symptoms such as swollen legs or breathlessness and to relieve fluid overload. They are widely recommended by guidelines and organisations such as the National Institute for Health and Care Excellence (NICE) in the UK. The loop diuretics available in the UK are …

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    • PII: S0002-9343(98)00111-9 - The American Journal of …

      https://www.amjmed.com/article/S0002-9343(98)00111-9/pdf

      The marked diuresis with the first dose of oral furosemide or torsemide in the present study demon-strates the efficacy of oral diuretics. A study of patients with renal insufficiency also supported this concept by demonstrating similar excretion rates of sodium with both oral and intravenous torsemide administration (15).

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    • [PDF File] Chronic Upper Respiratory Diuretics Commonly Tract …

      https://assets.ctfassets.net/4dmg3l1sxd6g/2u5EFCIrHba1d0MlFC5VFj/363765f61c001201cd6d1f90f8d62962/RxSol_DiureticsCommonlyUsedinDogs_Cats.pdf

      Loop Diuretics Loop diuretics, such as furosemide, bumetanide, and torsemide, inhibit the sodium-potassium-chloride (Na-K-Cl) symporter in the luminal membrane of the thick ascending limb of the loop of Henle, which induces the countercurrent multiplier efect. Inhi-bition of sodium reabsorption induces osmotic diuresis in more distal sections of the …

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    • The Changing Role of Loop Diuretics in Heart Failure …

      https://mdpi-res.com/d_attachment/jcm/jcm-13-01674/article_deploy/jcm-13-01674.pdf?version=1710418196

      The first loop diuretics (specifically, ethacrynic acid and furosemide) were developed in the first years of the 1950s and released about ten years later, leading to their prescription in several diseases characterized by edema, such as heart failure, nephrotic syndrome, and liver failure/cirrhosis [15–17].

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    • [PDF File] CHAPTER 7 Loop Diuretics - Springer

      https://link.springer.com/content/pdf/10.1007/978-3-642-79565-7_7.pdf

      e Chap. 8, this volume). These, consequently, have been named "low-ceiling" diuretics. Loop diuretics comprise a chemic lly heterogeneous group. Ph en oxyacetic acid type diuretics, such as ethacrynic acid and indacrinone (Fig. 1), mercurial diuretics, furosemide-related drugs, and several oth

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    • [PDF File] LOOP DIURETICS IN HEART FAILURE: EVIDENCE …

      https://wiadlek.pl/wp-content/uploads/archive/2021/WLek202104136.pdf

      The current guidelines do not have a clear answer to the question of which of the modern loop diuretics has advan-tages when used in patients with HF. At the current stage, the question of choosing the best loop diuretic remains de-batable [2, 3]. Furosemide appeared on the pharmaceutical market earlier than torasemide. As a result, experience …

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    • [PDF File] A Survey On Doctors’ Perceptions On The Efficacy Of Loop …

      https://www.iosrjournals.org/iosr-jdms/papers/Vol23-issue3/Ser-4/E2303042328.pdf

      Loop diuretics like furosemide and torsemide are commonly prescribed for fluid control in heart failure patients. Despite the wide usage of these drugs, understanding the perspectives and practices of Nigerian doctors regarding these loop diuretics in heart failure management is crucial.

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    • The Effects of the Loop Diuretics Furosemide and …

      https://www.jstage.jst.go.jp/article/jvms/65/10/65_10_1057/_pdf

      Therefore, animals with congestive heart failure require management with diuretics, such as thiazide, bumetanide, and furosemide. Furosemide is the diuretic most frequently given for edema. Although torasemide has beneficial effects in chronic congestive heart failure in humans [8], there are fewer clinical reports than on furosemide.

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    • Overview of Diuretic Strategies in Edematous States

      https://jdc.jefferson.edu/cgi/viewcontent.cgi?article=1267&context=tmf

      Limited cardiac output in heart failure decreases loop diuretic secretion into the tubular lumen from decreased renal perfusion, while cirrhosis through renal vasoconstriction. The mainstay diuretic in managing moderate-volume ascites in cirrhosis is either spironolactone (50-200 mg/day) or amiloride (5-10 mg/ day) with low doses of furosemide ...

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    • Comparison of loop diuretics in patients with chronic renal

      https://www.kidney-international.org/article/S0085-2538(15)34116-8/pdf

      Comparison of loop diuretics in patients with chronic renal insuffi-ciency. Furosemide and bumetanide share a number of characteristics including reduced natriuretic effects in azotemic patients. It has been presumed that this condition affects each drug equally, Previous stud-ies, however, suggest dissimilar pathways of delivery to their sites of

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    • [PDF File] Comparative effects of furosemide and other diuretics in the …

      https://link.springer.com/content/pdf/10.1007/s10741-020-10003-7.pdf

      Loop diuretics such as furosemide, bumetanide, and torasemide work through inhibiting the sodium, potassium, chloride (Na+/K+/ 2Cl−) co-transporter in the thick ascending limb of loop of Henle [4]. Hence, they decrease fluid overload symptoms, improve pulmonary congestion [5], and alleviate dyspnea [6].

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    • [PDF File] 2016-0506_NAVCInst_Cardiac Pt2_author.indd

      https://todaysveterinarypractice.com/wp-content/uploads/sites/4/2016/05/TVP_2016-0506_NavcInst-Cardiac-Pt2.pdf

      Diuretics are a critical component of the pharmaco-therapy of congestive heart failure (CHF). In humans with heart failure, 90% receive at least one diuretic.1 Of these, loop diuretics—furosemide, bumetanide, and torsemide—are the most potent and commonly used diuretics.

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    • [PDF File] 2016-0102_NAVCInst_CardiacMed_author.indd

      https://todaysveterinarypractice.com/wp-content/uploads/sites/4/2016/05/TVP_2016-0102_NavcInsti-Torsemide.pdf

      Diuretics are a critical component of the pharmacotherapy of congestive heart failure (CHF) (typically pulmonary edema or ascites). In humans with heart failure, 90% receive at least one type of diuretic.1 Of these, loop diuretics—furosemide, bumetanide, and. torsemide—are the most potent and commonly.

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