Lorazepam oral to iv equivalent
[PDF File] UC J D H D P M E M O R A N D U M To: RE - UConn Health
http://5y1.org/file/21877/uc-j-d-h-d-p-m-e-m-o-r-a-n-d-u-m-to-re-uconn-health.pdf
o Oral lorazepam and diazepam can be used at equivalent doses to IV formulations For seizures, benzodiazepines are 1st line. o IV/IM lorazepam remains first line while supply is available o In units where IV/IM midazolam and diazepam are available for use, IM midazolam 10mg is the preferred alternative agent. ...
[PDF File] COMPARISON OF THE ACTIONS OF DIAZEPAM AND …
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diazepam 10 mg is equivalent to lorazepam 2-2.5 mg. Diazepam is better absorbed after oral than after i.m. administrations but this does not apply to lorazepam. The clinical effect and amnesia begin more rapidly with diazepam, but last longer following lorazepam. Lorazepam is more effective than diazepam in blocking the emergence sequelae from ...
[PDF File] ATIVAN (lorazepam) Injection - Food and Drug …
http://5y1.org/file/21877/ativan-lorazepam-injection-food-and-drug.pdf
Following a single 2-mg oral dose of 14C-lorazepam to 8 healthy subjects, 88±4% of the administered dose was recovered in urine and 7±2% was recovered in feces. The percent of administered dose recovered in urine as lorazepam glucuronide was 74±4%. Only 0.3% of the dose was recovered as unchanged lorazepam, and the remainder of the
[PDF File] ATIVAN Injection (lorazepam injection, USP) - Food and …
http://5y1.org/file/21877/ativan-injection-lorazepam-injection-usp-food-and.pdf
Lorazepam is extensively conjugated to the 3-O-phenolic glucuronide in the liver and is known to undergo enterohepatic recirculation. Lorazepam glucuronide is an inactive metabolite and is eliminated mainly by the kidneys. Following a single 2-mg oral dose of . C-lorazepam to 8 healthy subjects, 88±4% of the administered dose
[PDF File] Benzodiazepines: ALGORITHM Tapering and Prescribing
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Oral Dose Equivalences of Common BZRAs Trade Name Relative Potency (mg)* Dosages available as immediate release tablets es Chlordiazepoxide Alprazolam Xanax 0.5 0.25mg, 0.5mg, 1mg, 2mg Librium 10 Clonazepam Klonopin 0.25-0.5 0.5mg, 1mg, 2mg Diazepam Valium 5 2mg, 5mg, 10mg Lorazepam Ativan 1 0.5mg, 1mg, 2mg Oxazepam Serax 15-30
[PDF File] Guidelines for Antipsychotic Medication Switches
http://5y1.org/file/21877/guidelines-for-antipsychotic-medication-switches.pdf
to 15 times the oral dose, every 4 weeks Oral fluphenazine to depot fluphenazine Accumulation occurs after approximately 3 weeks of depot therapy. Multiply the total daily dose by 1.2 and give as fluphenazine decanoate IM every one to two weeks. Increase the dose interval to 3 weeks or so after 4 to 6 weeks of therapy From depot to oral
[PDF File] HALOPERIDOL ADMINISTRATION – ORAL
http://5y1.org/file/21877/haloperidol-administration-oral.pdf
The maximum recommended daily dose for each route of administration is different, because parenteral doses generally have a greater bioavailability than oral doses. Maximum dose in 24 hours: If only oral form prescribed: 20mg If only IM form prescribed: 12mg If oral & IM forms prescribed in combination, refer to table below for total daily dose.
[PDF File] PO Alternatives to Commonly Prescribed IV Antibiotics (Those …
http://5y1.org/file/21877/po-alternatives-to-commonly-prescribed-iv-antibiotics-those.pdf
Automatic IV to PO Switches Approved per P&T Protocol: Intravenous Medication Oral Conversion Levofloxacin 750mg IV Levofloxacin 750mg PO Ciprofloxacin 400mg IV Ciprofloxacin 500mg PO Ciprofloxacin 200mg IV Ciprofloxacin 250mg PO Azithromycin 500mg IV Azithromycin 500mg PO Azithromycin 250mg IV Azithromycin 250mg PO
[PDF File] A method to establish lorazepam milligram equivalent (LME) …
http://5y1.org/file/21877/a-method-to-establish-lorazepam-milligram-equivalent-lme.pdf
Two common equivalent sedative unit choices are diazepam and lorazepam. Diazepam (Valium) and lorazepam (Ativan) are most often dose equilibrated as 10mg of diazepam = 1mg of lorazepam. For the purposes of NarxCare, lorazepam has been chosen as the comparison sedative for all other sedative medications. Analogous to opioids and their …
[PDF File] Intravenous to Oral Therapy Conversion - FormWeb
http://5y1.org/file/21877/intravenous-to-oral-therapy-conversion-formweb.pdf
Ideal Characteristics of Oral Medications Included in an IV to PO Conversion Program • Should have excellent bioavailability (ideally greater than 80%) • Should be well tolerated upon administration • Availability of multiple dosage forms (e.g., tablets and liquids) • Dosing at a frequency equivalent to or less than the IV formulation
[PDF File] Table 1. Opioid, benzodiazepine, neuromuscular blockade, …
http://5y1.org/file/21877/table-1-opioid-benzodiazepine-neuromuscular-blockade.pdf
IV midazolam 1 mg IV lorazepam 0.5 mg Neuromuscular Blockers Equivalent Dose IV vecuronium 1 mg IV cisatracurium 1 mg NSAIDs Equivalent Dose IV ketorolac 1 mg Oral ibuprofen 20 mg Oral naproxen 45 mg Oral aspirin 7 mg Steroids Equivalent Dose IV hydrocortisone 1 mg IV dexamethasone 0.025 mg IV methylprednisolone 0.20 mg Oral …
[PDF File] Converting oral to intravenous or subcutaneous infusions
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Dornase alpha, 2.5mg, neb, BD. Midazolam 2mg, IV/SC, PRN max hourly = 0.4(oral bioavailability) x 5mg. Midazolam infusion 6mg/24 hours IV = 0.4 x 15mg (total dose in last 24h) Morphine infusion 15mg/24 hours IV = 0.5 (oral bioavailability) x 30mg (total dose in last 24h) Morphine bolus 2.5mg IV/SC PRN max hourly = 1/6 of infusion.
[PDF File] IV to PO Pharmacy Conversion Protocol - FormWeb
http://5y1.org/file/21877/iv-to-po-pharmacy-conversion-protocol-formweb.pdf
Inclusion Criteria for IV to PO Conversion: Infections that Require IV Antibiotics. Must satisfy below criteria: Tolerate oral diet or enteral nutrition and/or receiving oral medications. Infection does not require IV antibiotics. Afebrile (< 100.4 ̊F in the last 24 hours) Received ≥ 24 hours of IV antibiotics.
[PDF File] LORAZEPAM INTENSOL™ Oral Concentrate USP 2 mg per
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W SUPPLIED2 mg per mL IntensolTM Oral Concentrate USPNDC 0054-3532-44: Bottles of 30 mL with calibrated dropper (graduations of 0.25 mL [0.5 mg], 0.5 mL [1. g] and 1 mL [2 mg] on the dropper).PROTECT FROM LIGHTStore at Cold Temperature–Refrigerate 2°-8°C (36°-46°F) Dispense only in th.
[PDF File] Microsoft Word - Benzodiazepine equivalents Aug 2014.doc
http://5y1.org/file/21877/microsoft-word-benzodiazepine-equivalents-aug-2014-doc.pdf
Lorazepam Intermediate 0.5 - 1mg Ativan 1mg, 2.5mg S4 Nitrazepam Long 5mg Alodorm, Mogadon 5mg S4 Oxazepam Short 30mg Alepam, Murelax, Serepax 15mg, 30mg S4 Temazepam Short 10 - 20mg Normison, Temaze, Temtabs 10mg S4 Triazolam Very short 0.25mg Halcion 0.125mg S4 Zolpidem Very short 10mg Dormizol, Somidem, Stildem, …
[PDF File] Lorazepam vs Midazolam for Acute Agitation - The Pharm …
http://5y1.org/file/21877/lorazepam-vs-midazolam-for-acute-agitation-the-pharm.pdf
emergency department, lorazepam and midazolam for acute agitation. Pharmacology Lorazepam Midazolam Administration IV IM IV IM IN Dose* Sedation: 0.5-2 mg Sedation: 0.5-2mg Sedation: 0.5-2mg Sedation: 2.5-5mg Sedation: 0.1mg/kg Onset 2-10 min (longer for anticonvulsant) 20-30 min 3-5 min 5-15 min 10 min Duration 3 – 6 hours for
[PDF File] CORTICOSTEROID EQUIVALENCY TABLE (ORAL OR IV) …
http://5y1.org/file/21877/corticosteroid-equivalency-table-oral-or-iv.pdf
CORTICOSTEROID EQUIVALENCY TABLE (ORAL OR IV) Equivalent Dose (mg) Glucocorticoid (Anti-inflammatory) Mineralocorticoid (Na+-Retaining) Short Acting Hydrocortisone (Cortisol) 20 1 2 Intermediate Acting Fludrocortisone - 10 125 Prednisone 5 4 1 Prednisolone 5 4 1 Methylprednisolone 4 5 0 Long Acting Dexamethasone 0.75 25 0 …
[PDF File] Nil by Mouth Guidance for Patients with Epilepsy/Seizures
http://5y1.org/file/21877/nil-by-mouth-guidance-for-patients-with-epilepsy-seizures.pdf
Table 2: Guidance for conversion of other oral anti-epileptic drugs2,3 Drug name Oral formulation Alternative formulations Dosage equivalence Method of administration in NBM patients Brivaracetam Tablets 4 Liquid 10mg/ml Injection (IV) Equivalent dose (all formulations) Use liquid for patients with NG/PEG tubes (licensed).
[PDF File] AMNEAL RECEIVES FDA APPROVAL FOR LORAZEPAM ORAL …
http://5y1.org/file/21877/amneal-receives-fda-approval-for-lorazepam-oral.pdf
Lorazepam Oral Concentrate is indicated for the management of anxiety disorders or for short-term relief of anxiety symptoms or anxiety associated with depressive symptoms. Amneal began shipping Lorazepam Oral Concentrate in the 2 mg/ml strength as a clear, flavorless liquid easily mixed with another liquid or semi-solid food on March …
[PDF File] tableau comparatif BZD et switch rupture - CHUV
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Tableau comparatif des benzodiazépines et agonistes aux récepteurs des benzodiazépines & Principes généraux lors de passage d’une molécule à l’autre. Ruptures d’approvisionnement : Les pénuries de médicaments et leur durée évoluent quotidiennement et peuvent varier d’une pharmacie (hospitalière/ville) à l’autre en ...
[PDF File] New Zealand Data Sheet - Medsafe
http://5y1.org/file/21877/new-zealand-data-sheet-medsafe.pdf
ATIVAN (lorazepam) is useful in the therapy of most disorders in which anxiety is a major component. Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic. Treatment of moderate to severe anxiety. Treatment of insomnia associated with anxiety.
[PDF File] Intravenous to Oral Conversion for Antimicrobials - Northern …
http://5y1.org/file/21877/intravenous-to-oral-conversion-for-antimicrobials-northern.pdf
70%. Clindamycin 600 mg IV q8h. Clindamycin 450 mg PO TID. 90%. Fluconazole IV once daily (daily dose same for both IV and PO administration) Fluconazole po once daily (daily dose same for both IV and PO administration) 90%. Levofloxacin 750 mg IV q24h Levofloxacin 500 mg IV q24h. Levofloxacin 750 mg PO daily Levofloxacin 500 mg PO daily.
[PDF File] Appendix I -Intravenous (IV) TO Oral (PO) Dose Conversion
http://5y1.org/file/21877/appendix-i-intravenous-iv-to-oral-po-dose-conversion.pdf
Conversion of IV to PO ranges from 1:1 to 1:1.5 Oral bioavailability about 60% for tablets and oral solution. 1,4,5 hydrocortisone variable variable Suggest consulting pharmacist for appropriate conversion Oral bioavailability greater than 90% 2,4 HYDROmorphone 2 mg IV 4 mg IR oral formulation Opioid IV to oral requires clinical assessment ...
[PDF File] OWNER PAGE DATE REVIEWED APPROVED BY POLICY …
http://5y1.org/file/21877/owner-page-date-reviewed-approved-by-policy.pdf
Pharmacists review the IV to PO patient list daily to identify potential candidates for IV to PO conversion based upon established criteria. All ADULT patients on any IV medications listed below are considered eligible for IV to PO conversion and should be assessed. Antibiotics. Antihistamines. Vitamins.
[PDF File] Oral lorazepam can be substituted for intravenous …
http://5y1.org/file/21877/oral-lorazepam-can-be-substituted-for-intravenous.pdf
to an effect-equivalent dose of oral medication within the same therapeutic class when the patient is due to be discharged to the general ward without cardiorespiratory monitoring, when intravenous access is no longer required or available or when prolonged weaning is expected. The initial daily dose of oral lorazepam is calculated by dividing
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