Losartan hctz 50 12 5 recall
What is the mechanism of action of losartan?
Losartan is an orally active agent that undergoes substantial first-pass metabolism by cytochrome P450 enzymes. It is converted, in part, to an active carboxylic acid metabolite that is responsible for most of the angiotensin II receptor antagonism that follows losartan treatment.
What is general losartan potassium?
Pharmacokinetics General Losartan Potassium Losartan is an orally active agent that undergoes substantial first-pass metabolism by cytochrome P450 enzymes. It is converted, in part, to an active carboxylic acid metabolite that is responsible for most of the angiotensin II receptor antagonism that follows losartan treatment.
How long does it take for losartan to peak?
Mean peak concentrations of losartan and its active metabolite are reached in 1 hour and in 3hours, respectively. While maximum -4 plasma concentrations of losartan and its active metabolite are approximately equal, the AUC of the metabolite is about 4 times as great as that of losartan.
What is a Class 1 drug recall?
Class 1 Recall: Reasonable probability that using the drug will cause serious adverse health consequences or death. Class 2 Recall:Using the drug may cause temporary or medical reversible adverse health consequences, the probability of serious adverse health consequences is remote.
[PDF File]Losartan Potassium and Hydrochlorothiazide PI
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Losartan potassium and hydrochlorothiazide tablets 50 mg/12.5 mg, losartan potassium and hydrochlorothiazide tablets 100 mg/12.5 mg, and losartan potassium and hydrochlorothiazide tablets 100 mg/25 mg combine an angiotensin II receptor (type AT1) antagonist and a diuretic, hydrochlorothiazide.
[PDF File](LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE …
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50/12.5 (LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE TABLETS) HYZAAR ® 100/12.5 (LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE TABLETS) HYZAAR ® 100/25 (LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE TABLETS) WARNING: FETAL TOXICITY • When pregnancy is detected, discontinue HYZAAR ® as soon as possible. •
[PDF File]HYZAAR 50/12.5 (LOSARTAN POTASSIUM AND …
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HYZAAR® 50/12.5(LOSARTAN POTASSIUM AND HYDROCHLOROTHIAZIDE T... Page 3 of 30 with these diuretics. The mechanism of the antihypertensive effect of thiazides is unknown. Pharmacokinetics General Losartan Potassium Losartan is an orally active agent that undergoes substantial first-pass metabolism by cytochrome P450
URGENT: Recalls, Market Withdrawals, & Safety Alerts
UPC: 3 49597 00044 5 2PA20021, 2PA20061; D-160, D-155, D-162; 7PA20071 Class II pH-D Feminine Health Riomet ER (metformin hydrochloride for extended-release oral suspension) 500 mg per 5 mL 16 oz. For Oral Use NDC: 10631-0019-17 AB06381 Exp. 10/2021 Class II SUN PHARMACEUTICAL INDUSTRIES INC Losartan Pot/HCTZ 50/12.5 mg Tablets
[PDF File]ARB Recall Affecting Your Practice?
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Losartan 50mg 142 Losartan 100mg 136 Losartan/Hydrochlorothiazide (HCTZ) 50mg/12.5mg 55 Losartan/Hydrochlorothiazide (HCTZ) 100mg/12.5mg 36 Losartan/Hydrochlorothiazide (HCTZ) 100mg/25mg 74 Valsartan 40mg 24 Valsartan 80mg 62 Valsartan 160mg 75 Valsartan 320mg 69 Valsartan/Hydrochlorothiazide (HCTZ) 80mg/12.5mg 26
[PDF File]Torrent – Recall of losartan/hydrochlorothiazide
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Torrent – Recall of losartan/hydrochlorothiazide • On January 22, 2019, Torrent announced an expansion of their voluntary, consumer-level recall of losartan tablets to include several lots of losartan/hydrochlorothiazide (HCTZ) tablets due to the detection of trace amounts of an unexpected impurity, identified as N-nitrosodiethylamine (NDEA),
[PDF File]Losartan Recall - University of Saskatchewan
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Losartan Recall Due to the presence of a potentially carcinogenic contaminant: N-nitroso-N-methyl-4-aminobutyric acid (referred as “NMBA”), Health Canada has recalled Teva-Losartan / HCTZ 50/12.5mg. As a precaution, Teva, Apotex, Pharmascience, and Pro-Doc have voluntarily recalled other losartan products. For details
[PDF File]Torrent – Recall of losartan- containing products
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Losartan/HCTZ : 50 mg/12.5 mg . 13668-116-90 : BEF7D051 (11/30/2020) Losartan/HCTZ : 100 mg/25 mg . 13668-118-90 : 4P04D007 (7/31/2020) • Losartan and losartan/HCTZ tablets are used for the treatment of hypertension (HTN) and to reduce the risk of stroke in patients with HTN and left ventricular hypertrophy. Losartan tablets are also
[PDF File]Losartan Potassium Tablets and Losartan Potassium ...
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Drug recall notice for Losartan Potassium Tablets and Losartan Potassium Hydrochlorothiazide tablets ... candesartan/hctz, irbesartan, irbesartan/hctz, olmesartan, olmesartan/hctz, telmisartan, telmisartan/hctz, ... 50mg/12.5mg, 90 count BEF7D010 4/30/2020 13668-116-90
RPMS - Indian Health Service | Indian Health Service (IHS)
5 4377902a risperidone 1mg 30 a 01-08 01-14 2 30. 6 8066436 rofecoxib 12.5 mg tab 30 e 09-15 09-15 2 30. 7 8071393 simvastatin 20mg 30 a 03-24 03-24 2 30. 8 8062318a triamcinolone acetonide 100mcg/inh 20g a 01-08 01-14 1 30. qty: 1
[DOCX File]fellow.berlinpharm.com
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His current medications include aspirin 81 mg daily, simvastatin 40 mg daily, warfarin 5 mg daily, lisinopril 10 mg daily, carvedilol 6.25 mg twice daily, furosemide 40 mg daily, and digoxin 0.25 mg daily.Laboratory data at this time include: a sodium of 135 mEq/L, potassium of 4.3 mEq/L, serum creatinine of 0.9 mg/dl, an INR of 2.4, and a digoxin concentration of 0.9 ng/ml. Vital signs ...
[DOCX File]Veterans Affairs
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FedBizOppsCombined Synopsis/Solicitation Notice*******CLASSIFICATION CODESUBJECTCONTRACTING OFFICE'S ZIP-CODESOLICITATION NUMBERRESPONSE DATE (MM-DD-YYYY)ARCHIVE DAYS AFTER THE RE
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PAGE 1 OF1. REQUISITION NO. 2. CONTRACT NO.3. AWARD/EFFECTIVE DATE4. ORDER NO.5. SOLICITATION NUMBER6. SOLICITATION ISSUE DATEa. NAMEb. TELEPHONE NO. (No Collect ...
[DOC File]ARIC - Home | CSCC
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Specify type in 5d. on the paper form or check “Other” in 5.d.7. and specify type in 5.d.7.a.on the data management system (DMS) screen. If “cardiomyopathy” is stated with no adjective preceding it, enter “Unspecified” in 5.d. on the paper form or check “Other” in 5.d.7. and state “Unspecified” in 5.d.7.a. in the DMS. It is acceptable to record specific qualifiers as you ...
[DOC File]www.title24uscode.org
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Of the estimated 50 million, 166 out of 1,000, with unhealthy levels of lipoprotein in their blood, 7 million Americans feel angina (23 in 1,000), 1.5 million will suffer an acute myocardial infarction (heart attack) for which 550,000 will be hospitalized (1.8 out of 1,000) and of the 2.4 million people who died in 2004, 666,000 died from heart disease (2.2 out of 1,000) and 150,000 from ...
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