Low iron high ferritin anemia
[DOC File]Laboratory Evaluation of Microcytic Anemia
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Unlike serum iron levels, serum ferritin value is not affected by recent iron therapy. However, it is also an acute phase reactant protein that is elevated in response to infection. Therefore, only an unequivocal low ferritin level in CRP negative (< 5 mg/L) patient can be used to make the diagnosis of iron …
[DOC File]Indicators for assessment of anemia and iron deficiency in ...
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prevents iron absorption in duodenum and release from macrophages. Other cytokines – lead to impaired proliferation of progenitor cells and blunted response to EPO. Labs – low serum iron, normal/elevated serum ferritin, decrease EPO. Anemia & Location of Destruction . …
Ferritin Blood Test: Discover Results and Normal Levels
Recall that iron is normally stored as ferritin, but in iron deficiency, the “stores” of ferritin are “depleted”—otherwise there would be no deficiency of iron; in contrast, the stores of ferritin are elevated in anemia of chronic disease; that is, there is plenty of iron in the body (stored in the liver and spleen, for example) but it is “entrapped” with the macrophages; that is ...
OHIO Open Library
Ferritin has a high sensitivity and specificity for IDA when a cut-off of ≤30 µg/L is used.2 Though ferritin is an acute phase reactant, studies have demonstrated that the majority of patients with concomitant IDA and a chronic inflammatory or liver disease will be classified as iron deficient employing these criteria.2,3 In the small subset ...
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