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[DOC File]Anti-ssDNA Is Not a Useful Diagnostic Test
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There were no lesions on the head or neck or other locations. The patient’s ANA was positive at a titer of 1:40, in a speckled pattern, and SS-A antibody was positive at 1.4 (nl < 1.0). Histopathology was consistent with subacute cutaneous lupus erythematosus. Conclusion:
diagnosing lupus with negative ana

[DOC File]Rovner - University of New England
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Antinuclear antibodies (ANA) are frequently present in patients with systemic lupus erythematosus (SLE) and, less commonly, in other autoimmune diseases Rheumatoid arthritis, Collagen vascular diseases, chronic liver diseases and systemic sclerosis (scleroderma). ANA bind to several nuclear antigens including DsDNA, SSDNA, RNP, Sm, SSA and SSB.
next step after positive ana

What Is ANA-Negative Lupus?
Systemic lupus erythematosus is usually diagnosed following identification of circulating autoantibodies commonly including anti-nuclear (ANA), double-stranded DNA and anti-Smith antibodies. This patient had an ANA titre of 1/160 (common in the general population) and was negative for these other antibodies. The kidney is commonly involved. 1
autoimmune disease with negative ana

[DOCX File]ANA Testing Pathology Quick Guide - Wandsworth CCG
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ANA negative lupus +SSA, SSB antibodies (anti Ro, anti La) less cardiac, renal involvement compared to SLE. small, annular red plaques in sun exposed areas. Neonatal lupus: (infants born to mothers with SCLE) 30 heart block. discoid lesions. anemia, "HELP" syndrome (Hepatic Enzymes Low Platelets)
ana test conditions it may diagnose

[DOC File]ANA Screen IgG by ELISA - Atlas Link, Inc
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Testing for antibodies against nuclear antigens can be helpful in the diagnosis of diseases such as systemic lupus erythematosus and scleroderma. The National Consensus Conference on Guidelines for ANA testing was published by Kavanaugh et al. in January, 2000.1 Those Guidelines stress that improper use of ANA testing can lead to misinformation ...
ana test positive

[DOCX File]University of Edinburgh
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ANA alone has a low positive predictive value for SLE so it is unlikely to be useful in patient populations with a low prevalence of systemic lupus erythematosus (e.g. the elderly). A negative ANA test does not rule out systemic lupus erythematosus – if you have strong clinical indications, contact the lab for …
ana negative lupus criteria

Lupus with a negative ana