Major drug interactions with warfarin
[DOC File]TEMPLATE
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3. Drug interactions: There is a very large range of possible drug interactions that may increase or decrease the activity of warfarin (and hence increase or decrease the INR). These may not necessarily contraindicate use, rather careful dosage adjustment may be all that is required,. Check carefully when prescribing . 4. Skin necrosis reactions:
[DOCX File]3. Medications Altering Warfarin Pharmacokinetics and ...
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By day five, if patient is still subtherapeutic, you should evaluate for lab error, missed doses, drug interactions, dietary or pharmaceutical vitamin K intake, and active disease states. True warfarin resistance does occur, but is quite rare.
[DOC File]Workshop 4: Drug Interactions
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Warfarin is a narrow therapeutic range drug. small increases in blood level can lead to haemorrhage including stroke. small decreases in blood level can result in blood clots (stroke, DVT, PE) Ciprofloxacin inhibits the metabolism of many medicines. Workshop 4.2: Drug Interactions
[DOC File]APPENDIX C - Maine
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food and drug interactions. this section is to assist the crma in choosing appropriate foods to mix medications with when needed, and to help them recognize what major foods interact with the major classifications of drugs utilized in the residential care setting.
[DOC File]Tennessee Pharmacist Coalition on Medication Safety ...
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The facility’s warfarin management practices include: Notification of dietary services when a patient is receiving warfarin therapy. Automatic nutrition consults when patients are first placed on warfarin to avoid drug-food interactions. Warfarin is dispensed in unit dose only (e.g., warfarin …
PennState Geisinger Health System
Warfarin drug-drug interactions. Warfarin drug-food interactions. PT/INR testing . Embolic and hemorrhagic events. Low-molecular weight heparins. Cardiology: Acute Coronary Syndromes. ... Major symptoms/Clinical presentation. Diagnostic laboratory tests. Prognosis: treated and untreated. Drug Therapy: THIS IS THE MAJORITY OF YOUR PRESENTATION ...
[DOC File]The Drug Store
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Drug interactions (used with permission from 1) Drug A Drug B What could happen Notes Warfarin NSAID, ASA Bleeding Avoid use together Warfarin Tylenol Bleeding Risk is not as great as NSAID, minimal risk with one or two doses but ideally should be avoided Antidepressants (SSRIs) NSAID Increased risk of bleeding Watch for any increase in bleeding.
[DOC File]DRUG INTERACTIONS - Yola
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Drug interactions can occur inside or outside the body; called as in-vivo and in-vitro drug interactions. ... The absorption of warfarin is inhibited by heptabarbitone and that of griseofulvin by phenobarbitone. ... The liver is the major site for metabolism and excretion of drugs. The drugs capable of producing liver damage are classified into ...
[DOC File]Evidence Based Synthesis Program (ESP) - Comparative ...
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Drug interactions in the case of Warfarin are mainly through the CYP2C9 inhibiters and dietary Vitamin K, which is a long and inexhaustible list of drugs that interact with Warfarin. In case of oral anticoagulants it’s mainly the P-glycoprotein inhibitors, and in the case of Rivaroxaban the CYP3A4 inhibitors as well.
[DOC File]Drug - University of Washington
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Allergies No major issues Drug interactions May decrease warfarin clearance (significance unclear) Dose (renal/hepatic failure, obesity) 100 mg IV x1, then 50 mg IV q12 hours (x10-14 days) NO adjustment in renal dysfunction. In severe hepatic impairment, the …
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