Meropenem spectrum of activity
Meropenem. A review of its antibacterial activity ...
activity of meropenem-vaborbactam against gram-positive bacteria and anaerobes would be expected to be similar to that of meropenem. Mechanism of Resistance Although vaborbactam restores the activity of meropenem against class A carbapenemases, there are notable gaps in the spectrum of β-lactamase inhibition, including Ambler class B and class ...
[DOC File]Antimicrobial Pharmacotherapy in Children
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Potentiation of meropenem by OP0595 was weaker than for other partner -lactams. DISCUSSION. OP0595 has MICs of 0.5-4 g/ml for most . E. coli, Klebsiella, Enterobacter. and . Citrobacter. spp. isolates (1,2) but this activity, which reflects attack on PBP2, is vulnerable to mutational resistance (1).
[DOC File]General Outline for Antibiotics (a good study guide)
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Similarly, if their patient is receiving meropenem and they know this is a restricted antibiotic because it has such broad-spectrum activity, and they see “susceptible” next to several other antibiotic agents, they should feel comfortable asking the prescribing clinician if it might be reasonable to adjust the antibiotic therapy.
[DOCX File]AHRQ Safety Program for Improving Antibiotic Use
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Carbapenems associated with a cyclic amine group such as meropenem, doripenem, panipenem, and ertapenem are notably broader in their spectrum of activity against bacterial infections 7 Overall, ertapenem is limited in its spectrum of activity, meropenem is the least potent, and doripenem is highly stable against hydrolysis [
[DOC File]Gastroenterology - Stanford University
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This means that methicillin has a lower activity and a narrower spectrum of activity compared to penicillin G. Page reference: 399. a. There is an electron withdrawing group on the side chain, and so it is acid sensitive. b. It can be taken orally *c. It is less active than penicillin G. d. It has a broader spectrum of activity compared to ...
[DOCX File]Northwestern Medicine
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1. antimicrobial activity. a) broad spectrum “nuke-em” antibiotics. b) drugs of choice for serious infections, including those caused by Klebsiella, Enterobacter, Serratia, and Pseudomonas. c) lack activity against Listeria monocytogenes and penicillin- resistant pneumococci (agents of bacterial meningitis) 2.
[DOCX File]University of Pittsburgh
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Ertapenem’s antimicrobial spectrum more closely resembles that of ampicillin-sulbactam (see section below on (-lactamase and antimicrobial resistance) than that of the other carbapenems. Major side effect of concern: seizures. Risk appears lowest with meropenem and it is thus labeled for use in patients with meningitis.
[DOCX File]Welcome to UEA Digital Repository - UEA Digital Repository
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Acute necrotizing pancreatitis (involving more than 30% of pancreas) generally warrants broad spectrum antibiotics (e.g. imipenem or meropenem). Enteral feeding via nasojejunostomy tube should be attempted with high protein/low fat preparations if pts are NPO for more than 7-10 days. Consider TPN in patients who do not tolerate enteral feeding.
[DOCX File]Michigan Medicine | University of Michigan
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Antifungal Spectrum of Activity. Antifungal Spectrum of Activity. Antifungal Spectrum of Activity. Antibiotic Spectrum of Activity. Antibiotic Spectrum of Activity
[DOC File]Type content here… (Font: Arial, Size: 12)
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Patients with respiratory illnesses were particularly problematic as they often could not be switched to once daily antibiotics, due to lack of availability of appropriate agents with the correct spectrum of activity (namely cover for Pseudomonas sp).
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