Methotrexate for arthritis

    • Methotrexate: MedlinePlus Drug Information

      Methotrexate is a folic acid antagonist and is a disease modifying drug for rheumatoid arthritis Indications for the purposes of this guideline Treatment of adults with inflammatory joint disease and autoimmune disease.

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    • [DOC File]UKMi Q&A xx - SPS

      https://info.5y1.org/methotrexate-for-arthritis_1_9824a7.html

      The efficacy and toxicity of Methotrexate (MTX) monotherapy vs. MTX combination therapy with non-biologic disease-modifying anti-rheumatic drugs in rheumatoid arthritis: A systematic review and metaanalysis. Appendix 2. Efficacy. DMARD naïve, Parallel design .

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    • [DOC File]OPTIMAL DOSAGE AND ROUTE OF ADMINISTRATION OF …

      https://info.5y1.org/methotrexate-for-arthritis_1_e1cd87.html

      Oral methotrexate is licensed to treat adults with rheumatoid arthritis and is also widely used to treat other inflammatory arthritides and connective tissue diseases including adults with juvenile inflammatory arthritis. Overview Methotrexate is an anti-metabolite cytotoxic drug which inhibits DNA synthesis and cellular replication.

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    • [DOC File]IUPUI

      https://info.5y1.org/methotrexate-for-arthritis_1_5f6800.html

      29 Szanto E. Low-dose methotrexate in rheumatoid arthritis: effect and tolerance. An open trial and a double-blind randomized study. Scand J Rheumatol 1986; 15:97-102. Insufficient data for analysis. 30 Tascioglu F, Oner C, Armagan O. The effect of low-dose methotrexate on bone mineral density in patients with early rheumatoid arthritis.

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    • [DOC File]GMMMG

      https://info.5y1.org/methotrexate-for-arthritis_1_8f02c7.html

      Methotrexate is a first line disease-modifying-anti-rheumatic-drug (DMARD) for rheumatoid arthritis (1,2); It is an antifolate agent with a chemical structure similar to that of folic acid and folinic acid (3), but its exact mechanism of action in treating this condition is unclear (3, 4, 5).

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    • [DOC File]GUIDELINE FOR THE PRESCRIPTION AND MONITORING OF ...

      https://info.5y1.org/methotrexate-for-arthritis_1_01c7c6.html

      Methotrexate has been in use for decades to treat psoriasis and some cancers. In 1988, it gained FDA approval for the treatment of rheumatoid arthritis. Since then, it has been used to treat other types of rheumatic diseases, including psoriatic arthritis, lupus, some forms of childhood arthritis…

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