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[DOCX File]Australian public assessment for Pralatrexate
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Minimal to mild erythema was seen at injection sites following IV administration to dogs and intradermal administration to rats, but without any histopathological findings. ... the meaning is the same. ... the potential for false negative findings as a consequence of variable FDG avidity among tumour subtypes and/or variable resolution of PET ...

[DOCX File]Extract from the Clinical Evaluation Report for Pralatrexate
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Patients with renal impairment have been identified as a special population of interest and the sponsor submitted the protocol for a study in patients with advanced cancer and mild, moderate, and severe renal impairment (Study PDX-019). This study is in the earliest stages of enrolment and no data had been generated at the time of submission.

[DOC File]X
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Consolidated Statement - One source states that for clinical trials with longitudinal FDG-PET measurements as a primary endpoint might require a minimum tumor FDG-avidity based on the SUV (e.g., >4, tumor to background ratio of >1.5 hepatic mean) at baseline in order to remain on or to be eligible for participation on the study and have ...

[DOC File]X
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One source states that for clinical trials with longitudinal FDG-PET measurements as a primary endpoint might require a minimum tumor FDG-avidity based on the SUV (e.g., tumor SUV of > 1.5 x hepatic mean + 2 SD of hepatic mean using a 3 cm ROI to determine the mean) at baseline in order to remain on or to be eligible for participation on the ...

[DOC File]2nd Irish Congress of - Home --> IMJ
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The clinical picture of a newborn infected with enterovirus is usually that of a mild illness, but rarely overwhelming infection of many organs, including liver and heart may ensue. The risk of this severe illness is higher for the newborns infected during the first two weeks of life.We describe the clinical course of a mother and baby affected ...

[DOC File]xn--c1atere.xn--p1ai
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Lung cancer is the most common cancer worldwide, and the leading cause of cancer associated deaths in the United States.1 Similar to other cancer types, altered glucose metabolism by cancer cells has been exploited in the diagnosis and staging of lung cancer mainly through the use of 18fluorodeoxyglucose (FDG)-PET imaging of patients with ...

[DOCX File]UKIO – Multidisciplinary scientific congress and technical ...
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1) Barrington SF, Mikhaeel NG. When should FDG-PET be used in the modern management of lymphoma? Br J Haematol 2014; 164: 315–328. 2) Bartel TB, Haessler J, Brown TL et al. F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma. Blood 2009; 114: 2068–2076.

Mild fdg avidity meaning