Mild obstructive small airway disease

• [DOC File]COPD Management (Read Code H3)

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  A chronic progressive deterioration of small airway obstruction with little variation in lung function and incomplete reversibility. Spirometry essential. Usually over the age of 35 with a history of greater than 10 pack years of smoking (daily smokes x years of smoking divided by 20). Common (2x angina) but often undiagnosed. Post bronchodilator FEV1 < 80% of predicted and FEV1/FVC ratio < 0 ...

  examples of small airway disease

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• [DOCX File]spiral.imperial.ac.uk

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  The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004;350:2645–2653. N Engl J Med 2004;350:2645–2653. Hogg JC, Chu FS, Tan WC, Sin DD, Patel SA, Pare PD, et al. Survival after lung volume reduction in chronic obstructive pulmonary disease: insights from small airway pathology.

  mild obstructive lung disease

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• [DOC File]Interpretation of Pulmonary Function Tests

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  Although often said to be a measurement of small airways obstruction, the FEF25-75 is fairly non-specific and reductions can be seen with a number of non-obstructive diseases. Nevertheless, an isolated reduction in the FEF25-75 serves as an important clue to mild obstructive lung disease when the FEV1/FVC ratio is normal. This occurs, for example, in early COPD and in asthmatics when they are ...

  treatment for small airway disease

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• [DOCX File][P] Medicine Management & Administration

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  Airflow obstruction is the result of both small airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema). The relative contributions of each vary from person to person, and can be accompanied by partially reversible airways hyper-reactivity. B. Chronic bronchitis is defined by the presence of chronic productive cough for three months in each of two successive years. C ...

  small airways obstructive defect

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• [DOCX File]Abstract - University of Manchester

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  34. Zuwallack RL, Nici L. Modifying the course of chronic obstructive pulmonary disease: looking beyond the FEV1. Copd . 2012; 9: 637-648. 35. Hogg JC, Pare PD, Hackett TL. The Contribution of Small Airway Obstruction to the Pathogenesis of Chronic Obstructive Pulmonary Disease. Physiol Rev . 2017; 97: 529-552. 36. Harvey BG, Strulovici-Barel Y ...

  small airway disease copd

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• [DOCX File]Abstract - Imperial College London

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  Although the degree of obstruction has been used to distinguish mild disease, no currently accepted definition exists for ‘early disease’ – due to lack of consensus on what constitutes ‘early’ and ‘disease’ in this context. Concepts of COPD have generally been derived from analysis of older individuals with established disease, emphasized incompletely reversible airflow ...

  chronic small airway disease

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