Monoclonal plasma cell disorder
[DOC File]University of the West Indies
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Multiple myeloma and related disorders R Monoclonal gammopathy Within 1 year of discovery R 2-5 years 55 After 5 years 0 Plasmacytoma Refer to Section Chief Other plasma cell disorders R LEUKOPLAKIA Leukoplakia, or smoker's patch (keratosis labialis) occurs as a white, thickened patch on the tongue and mucous membranes of the mouth.
[DOCX File]Pathophysiology and Clinical Presentation:
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Plasma cell neoplasms (consider the plasma cell neoplasm protocol) ... ___ Chronic lymphoproliferative disorder of NK cells ___ Aggressive NK-cell leukemia ... Mu Heavy Chain Disease: monoclonal cytoplasmic mu heavy chain+, B-cell antigen+, CD5-, CD10-, surface light chain-
[DOC File]NAME:
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plasma cell myeloma, or as Kahler's disease after Otto Kahler Myeloma is literally an “oma,” or tumor, involving the “myelo,” or blood-producing cells in the bone marrow. Malignant disease of the mature form of B lymphocyte, the plasma cell. Plasma cell secretes immunoglobulin, proteins necessary for antibody production to fight infection.
[DOCX File]Nonhodgkinlymphoma
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A. Plasma cells H. Thymus. B. Monoclonal I. Antibodies. C. Interferon J. Lymph. ... 7. _____ is a disease or disorder of the immune system caused by a retrovirus that enters the bloodstream and integrates its genes into the DNA of T cell lymphocytes. 8. The process in which macrophages engulf bacteria and other foreign materials that enter the ...
Neurologic aspects of plasma cell disorders.
Indolent lymphoproliferative disorder. IgM M-protein. Associated with hyperviscosity syndrome. Multiple Myeloma: Neoplastic monoclonal proliferation of bone marrow plasma cells, characterized by lytic bone lesions, plasma cell accumulation in the bone marrow and presence of monoclonal protein in serum &/or urine. Epidemiology:
[DOC File]M29-1, Part 5, L
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= A clonal B-cell malignancy characterised by abnormal proliferation of plasma cells able to produce a monoclonal immunoglobulin (M protein). Some myelomas only produce light chains, and a small percentage are non-secretory. near Complete Response = Normal electrophoresis but a positive immunofixation is defined as near-CR (n-CR)
[DOC File]The Hemic and Lymphatic Systems - Veterans Affairs
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Thalidomide, Lenalidomide and Bortezomib based regimens can be used to reduce monoclonal plasma cell population and light chain production. B. Light Chain Deposition Disease ... X-linked lysosomal storage disorder that results from absent or deficient activity of the enzyme -Galactosidase A (encoded by GLA gene on Xq22) progressive accumulation ...
[DOC File]Pharmacy Benefits Management Services Home
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Because they result from the proliferation of a single (i.e., monoclonal) plasma cell, the antibodies produced are termed monoclonal immunoglobulins or M-components. One particular type of M-component - Bence Jones protein - was named after its discoverer, Dr. …
[DOC File]Amyloidosis: An Overview
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Symptomatic multiple myeloma 100 Asymptomatic, smoldering, or monoclonal gammopathy of undetermined significance (MGUS). 0 ... Note (3): Rate residuals of plasma cell dysplasia (e.g., thrombosis) and adverse effects of medical treatment (e.g., …
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