Morphine to oxycodone conversion
[DOC File]OPIOID ANALGESIA – DRUG CONVERSIONS AT KIRKWOOD …
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Table 3: Results in patients with high percent urine oxymorphone Oxycodone dose qd oxymorphone (ng/ml) Oxycodone (ng/ml) %OM/OC 40 mg 916 912 99.5% 50 mg 450 324 138.9 80 mg 2,406 2,482 96.9 80 mg 4,634 4,802 96.5 240 mg 4,436 2,410 184.1 Discussion
Opioid conversion guide
Subcutaneous Morphine mg/day. Subcutaneous Oxycodone mg/day. Transdermal Fentanyl Patch µg/hour ÷ 2. x 5-10 ÷ 5-10. x 1.7 ÷ 1.7. x 10 ÷ 10. NOTE: The safest way to calculate opioid conversion is to convert to oral morphine and then convert back out again
[DOC File]Equianalgesic Chart (Changes in italics)
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Examples of dose conversion: NOTE: All drug conversions are approximate and care should be taken in conversion factors, especially at higher opioid doses. Zomorph PO to Diamorphine SC: 30mg Zomorph PO BD = 60mg Zomorph PO over 24 hours ÷ 3 = 20mg Diamorphine SC over 24 hours. Zomorph PO to Oxycodone PO:
[DOC File]Can fentanyl patches be abused
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Patient is not opioid-tolerant, defined as taking less than or equal to 60 mg of oral morphine daily, 20 mg of oral methadone daily, 30 mg of oral oxycodone daily, 8 mg of oral hydromorphone daily, or an equianalgesic dose of another opioid, for less than one week due to intolerance.
[DOC File]Drug Conversions
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Example conversion: Converting from morphine m/r 15mg bd to oral oxycodone: Total daily dose of morphine is 30mg. From Table 1, oxycodone potency equivalence = 1.5 – 2. Divide 30mg/1.5 = 20mg and 30mg/2 = 15mg. Therefore the approximate equivalent total daily dose of oral oxycodone is 15 - 20mg in divided doses.
[DOCX File]Opioids > 50 mg Morphine Equivalent Daily Dose (MEDD)
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5. The patient’s current dose of 240 mg per day of oral oxycodone is equal to 360 mg per day of oral morphine. The methadone conversion table indicates that a conversion factor for a DOMED of 360mg equals 8.3% or a 12 to 1 ratio of morphine to methadone. The patient’s DOMED of 360 mg is equal to 30 mg of methadone daily.
[DOC File]Jennifer P. Schneider M.D., PH.D.
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A common question is how to change a patient from oral morphine to a fentanyl patch. Fentanyl patches are indicated in patients with stable pain who have difficulty swallowing, unacceptable side effects with oral morphine or other opiates e.g. oxycodone; renal failure, persistent nausea and vomiting, gastrointestinal obstruction or poor compliance with oral medication
[DOCX File]Meeting began at 1:10 p
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Initial dose in opioid non-tolerant patients when converting from less than 30 mg morphine equivalents, and in mild to moderate hepatic impairment - 5 mcg/hr dose. When converting from 30 mg to 80 mg morphine equivalents - first taper to 30 mg morphine equivalent, then initiate with 10 mcg/hr dose.
[DOCX File]Date of check
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Morphine . Milligram Equivalent (MM. E) - A conversion of various opioids to a morphine equivalent dose by the use of accepted conversion tables. 13. Opioid – Any compound that binds to an opioid receptor in the central nervous system (CNS), including naturally occurring, synthetic or semi-synthetic, and endogenous opioid peptides. 14. Opioid ...
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