Muscular dystrophy causes
[PDF File]Muscular Dystrophies: What the radiologist should know
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–!Congenital Muscular Dystrophies: Diseases characterized by muscular weakness in early infancy (typically obvious at birth) and elevated CK in neonatal period (normalizes by 6-10 wks) –!Other Muscular Dystrophies: Heterogeneous group of diseases, which do not fit into the above two major categories
[PDF File]What Is Limb Girdle Muscular Dystrophy?
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What Is Limb Girdle Muscular Dystrophy? The muscular dystrophies are a group of muscle diseases which have three features in common: they are hereditary; they are progressive; and each causes a characteristic, selective pattern of muscle weakness. Limb girdle muscular dystrophy (LGMD) is the common name for a diverse group of muscular
[PDF File]Muscular dystrophy: basic facts
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Muscular dystrophy: basic facts - heterogenous group of inherited disorders characterized by progressive muscle weakness and wasting (regeneration of muscle tissue fails) - most apparent or symptomatic in skeletal muscle but heart and diaphragm muscle often involved (most patients die of heart failure or respiratory problems)
[PDF File]Statins and muscles
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muscle diseases, with very high levels in conditions like Duchenne muscular dystrophy. Many people can tolerate these symptoms, or they will improve with a lower dose of the same statin or changing to a different brand. The symptoms resolve if the statin is stopped. extremely rarely (probably in fewer than one in 10,000 people), statins
[PDF File]What is Myotonic Dystrophy - Muscular Dystrophy Association
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Myotonic dystrophy (DM) is a musculoskeletal disorder that affects the muscles and a number of different organs in the body. DM is the most common form of muscular dystrophy that begins in adulthood, usually in the 20s or 30s. It is a genetic disorder characterized by progressive muscle loss and weakness. DM causes weakness of the voluntary
[PDF File]Muscular Dystrophy: A Public Health Challenge
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Muscular Dystrophy: A Public Health Challenge Muscular Dystrophy • Muscular dystrophy refers to a group of inherited disorders that cause muscle weakness over time. This muscle weakness limits mobility and makes it difficult to perform many activities that are part of daily living. • Different types of muscular dystrophy affect different
[PDF File]causes muscular dystrophy and is effectively COL6A1 ...
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the most common congenital muscular dystrophy subtypes (1–4), and while supportive interventions such as nocturnal noninvasive ventilation have improved survival considerably (5, 6), there are no specific therapeutic interventions. Collagen type VI synthesis, secretion, and assembly in the extracellular space is a …
[PDF File]Facts About Rare Muscular Dystrophies
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What causes Muscular Dystrophy? All the forms of muscular dystrophy are inherited — that is, they're caused by mutations (mistakes) in a person's genes. Our genes are made of DNA and they reside in our chromosomes. Each gene contains the "recipe" for a different protein and its
[PDF File]Biomarkers for Duchenne muscular dystrophy: myonecrosis ...
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Duchenne muscular dystrophy (DMD) is a lethal, X-linked disease that causes severe loss of muscle mass and function in young children. Promising therapies for DMD are being developed, but the long lead times required when using clinical outcome measures are hindering progress. This progress would be facilitated by robust
[PDF File]What is Becker Muscular Dystrophy
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muscular dystrophy (DMD), which is caused by different mutations in the same gene. Because disease pro-gression and treatment plans differ between the two disorders, a BMD diagnosis should be confirmed with genetic testing. 1 A defining feature of BMD is a high degree of variability in symptoms— including onset, severity, and cor-
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