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[DOC File]label - Food and Drug Administration
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Drugs which interfere in the hepatic cytochrome P450 pathway, and consumption of grapefruit juice of in excess of 1 litre per day has been associated with non-autoimmune statin related myopathy(19), although an association with statin-induced necrotizing autoimmune myopathy is yet to be established. 5. Examination
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[DOCX File]Title: Statin Induced Autoimmune Myopathy
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Myopathy,↑liver transaminases. Reduces risk for acute coronary syndromes and stroke. Captopril ACE inhibitor; active drug, competitive;↓angiotensin II and aldosterone, so↓PVR and inhibits AT-mediated hypertrophy; 1st line treatment of CHF. and HTN. Also beneficial effects on serum lipids. Persistent cough, angioedema.
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[DOC File]Cardiovascular Drugs for Pharmacology Final
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Mitochondrial myopathy developing on treatment with the HMG CoA reductase inhibitors--simvastatin and pravastatin [letter]. Australian and New Zealand Journal of Medicine. 1995;25:374-5. 8.
drug induced myositis

[DOC File]Mitochondrial Dysfunction Brief: References
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There were no cases of myopathy seen with resins or niacin in this analysis. The authors concluded that there is an increased risk for myopathy in patients receiving lipid-lowering agents, with fibrates being associated with the greatest risk. However, the absolute risk of myopathy with lipid-lowering agents (statin and fibrates) is small.
drug induced myopathy

[DOC File]Medical Opinion – Penny D Hardy - medQuest LTD
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Muscle effects Myalgia, myositis, and myopathy have been reported with the statins; if myopathy is suspected and creatine kinase is markedly elevated (more than 5 times upper limit of normal), or muscular symptoms are severe, treatment should be discontinued; in patients at high risk of muscle effects, a statin should not be started if creatine ...
cardiomyopathy treatment drugs

[DOC File]Pharmacy Benefits Management Services Home
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According to its FDA-mandated drug label, Lipitor, like other Statin drugs, can cause skeletal muscle side effects such as myopathy and rhabdomyolysis, a condition characterized by atrophying skeletal muscle tissue. The lost muscle mass (myoglobin) collects in patients’ blood and can cause severe kidney problems and even death.
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[DOC File]Geriatric Assessment Tool Kit
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Additionally, higher doses of pitavastatin, concomitant use of fibrates, lipid-modifying doses of niacin or other clinically significant interacting drugs may further increase the risk of myopathy and/or rhabdomyolysis.
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[DOC File]STATIN-FIBRATE REPORT: Focus on Safety
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Date of first appropriate treatment for IIM (mm/yy): ____/____ Myositis Criteria . Criteria for diagnosis of PM/DM (check all that apply): ____Absence of other forms of myopathy, including inclusion body, metabolic, inherited or infectious forms ____Symmetric proximal muscle weakness ____Rash consisting of heliotrope and/or Gottron's papules/sign
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[DOC File]IMACS Form 01A: Core Patient Data - National Institute of ...
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3. Myopathy. can be caused by corticosteroids, or by antihyperlipidemics i.e. “statin” drugs. 4. Corticosteroids . used for many systems: pulmonary, rheumatology, dermatology, etc. suppression of the body’s immune response may be the therapeutic intent (post organ transplant, rheumatologic disease), or it may be an adverse effect
how do you treat myopathy

List of drugs/medicine used for Cardiomyopathy
Myopathy: Prolonged use of zidovudine has been associated with symptomatic myopathy [see Warnings and Precautions (5.2)]. Lactic Acidosis and Severe Hepatomegaly: Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues alone or in combination, including lamivudine ...
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Myopathy treatment drugs