Nature reviews neurology

    • [PDF File]The retina as a window to the brain—from eye research to ...

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      NATURE REVIEWS | NEUROLOGY ADVANCE ONLINE PUBLICATION | 3 e Light SC LGN Optic nerve Anterior chamber Vitreous humor Immunoregulatory molecules Lens d Inner blood–retinal barrier Pericyte Blood vessel Astrocyte endfeet Endothelial cell Tight junctions Müller cell process b Myelinated axon Axon Myelin sheath a Retinal ganglion cell c Injured ...

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    • [PDF File]The dizzy patient: don't forget disorders of the central ...

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      Nature Reviews | Neurology Spontaneous nystagmus Involuntary oscillatory eye movements with quick and slow phases that are elicited by an acute vestibular dysfunction. presents with the key symptom of acute vertigo (acute vestibular syndrome, or AVS), we recommend per­ forming the following five­step examination procedure

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    • [PDF File]Huntington disease: natural history, biomarkers and ...

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      NATURE REVIEWS | NEUROLOGY VOLUME 10 | APRIL 2014 | 205 statistical covariance for higher power to detect treatment effects. For biomarkers to be useful longitudinally, they must show consistent changes with progression of the disorder, and should predict some aspects of clinical pro - gression. They must also be responsive to therapeutics.

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    • [PDF File]Eye movements in patients with neurodegenerative disorders

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      NATURE REVIEWS | NEUROLOGY ADVANCE ONLINE PUBLICATION | 3 also been found for saccade testing using simple visu-ally guided paradigms, although a meta-analysis of 47 studies revealed an overall trend towards slightly pro-longed saccade latency in patients with PD compared with controls.20 By contrast, impaired initiation of sac -

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    • [PDF File]Rehabilitation and neuroplasticity in children with ...

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      used in children with unilateral cerebral palsy (UCP). CIMT was originally designed to address ‘learned disuse’ of the impaired hand after stroke in adults, but has since been adapted to aid ...

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    • [PDF File]NATURE REVIEWS | NEUROLOGY

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      NATURE REVIEWS | NEUROLOGY. Clinical manifestations of AD Sex differences in AD symptomatology have not been studied systematically. In the vast majority of reports of AD symptoms, data are not stratified by sex. The common practice of adjusting data by sex prevents

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    • [PDF File]SUPPLEMENTARY INFORMATION In format ... - Nature Research

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      SUPPLEMENTARY INFORMATION In format provided by Al Chalabiet al.(doi:10.1038/nrneurol.2016.182)! NATURE REVIEWS | NEUROLOGY www.nature.com/nrneurol

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    • [PDF File]NATURE REVIEWS NeURology 677 - Barbara Natterson …

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      NATURE REVIEWS NeURology. pre-verbal or nonverbal humans (such as the Behavioural Indicators of Infant Pain 8 and the Pain Assessment in Advanced Dementia scale 9) and for veterinary patients (such as the Short Form Glasgow Composite Measure Pain Scale for …

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    • [PDF File]The clinical use of structural MRI in Alzheimer disease

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      nature reviews | neurology volume 6 | FeBruarY 2010 | 69 Despite the evidence reported above, medial temporal atrophy is not sufficiently accurate on its own to serve as an absolute diagnostic criterion for the clinical diagnosis of aD at the mCi stage. High specificity is required to mini ‑ mize a false‑positive diagnosis of aD, and medial ...

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    • [PDF File]Nature Reviews journals

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      Nature Reviews journals The Nature Reviews editors commission leaders in the field to write articles of the highest quality, authority and acces sibility. With dedicated journals in the life sciences, clinical sciences and physical sciences, Nature Reviews provides a range of content for readers of every level, from

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