Nicardipine iv dosing
What is a bolus dose of IV nicardipine?
A bolus dose of IV nicardipine was adminis- tered 1,[80,83] 2 or 3[81,82] minutes prior to the start of laryngoscopy. Bolus doses of IV nicardipine attenuated the hypertensive responses to laryngoscopy and tracheal intubation in normotensive or hypertensive surgery patients who had undergone induction anaesthesia.
How is nicardipine hydrochloride administered?
Nicardipine hydrochloride injection is administered by slow continuous infusion at a concentration of 0.1 mg/mL. With constant infusion, blood pressure begins to fall within minutes. It reaches about 50% of its ultimate decrease in about 45 minutes.
How many mg of nicardipine are in a ML?
Each mL contains 0.2 mg nicardipine hydrochloride, 8.3 mg sodium chloride, USP, 0.0384 mg citric acid, anhydrous, USP, and 3.84 mg sorbitol, NF. Hydrochloric acid and/or sodium hydroxide may have been added to adjust pH to 3.7 to 4.7. The GALAXY container is fabricated from multilayered plastic (PL 2501).
How effective is IV nicardipine for intraoperative hypertension?
IV nicardipine provided effective, long-lasting treatment for intraoperative hypertension in patients undergoing abdominal surgery when administered as a 5mg bolus dose in a small, randomised, double- blind, placebo-controlled study. Patients had MAP >110mm Hg 5 minutes after an additional injection of fentanyl 4 g/kg.
[PDF File]HIGHLIGHTS OF PRESCRIBING INFORMATION infusion. When blood ...
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Recommended Dosing . Cardene I.V. is intended for intravenous use. Titrate dose to achieve the desired blood pressure reduction. Individualize dos age depending on the blood pressure to be...
Baxter Healthcare Corporation CARDENE IV- nicardipine ...
In patients with mild to moderate chronic stable essential hypertension, CARDENE I.V. (0.5 to 4 mg/hr) produced dose-dependent decreases in blood pressure. At the end of a 48-hour infusion at 4 mg/hr, the decreases were 26 mmHg (17%) in systolic blood pressure and 20.7 mmHg (20%) in diastolic blood pressure.
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Intravenous (IV) nicardipine (Cardene® IV), which demonstrates a relatively rapid onset/offset of action, is used in situations requiring the rapid control of blood pressure (BP). IV nicardipine was as effective as IV nitroprusside in the short-term reduction of BP in patients with severe or postoperative hypertension.
[PDF File]Injection: 200 mL nicardipine (0.2 mg/mL) in sodium chloride ...
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• When substituting for oral nicardipine therapy, use the intravenous infusion rate as follows (2.3): Oral Nicardipine Dose Equivalent IV Infusion Rate 20 mg q8h 0.5 mg/hr 30 mg q8h 1.2 mg/hr...
[PDF File]Intravenous Nicardipine Quick Reference Cardene®
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Initiate therapy at 5 mg/hour as a continuous IV infusion. The initial infusion rate of 5mg/hr IV may be increased by 2.5 mg/hr every 5 minutes to a maximum of 15 mg/hr, to maintain a SBP less than 220 mm Hg and DBP
[PDF File]Intravenous Nicardipine - EMCrit Project
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Jun 24, 2006 ·
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