Opioid dose conversion: free download. On-line document store on 5y1.org

[DOCX File]Opioids > 50 mg Morphine Equivalent Daily Dose (MEDD)
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Patient is not opioid-tolerant, defined as taking less than or equal to 60 mg of oral morphine daily, 20 mg of oral methadone daily, 30 mg of oral oxycodone daily, 8 mg of oral hydromorphone daily, or an equianalgesic dose of another opioid, for less than one week due to intolerance.
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[DOC File]Equianalgesic Chart (Changes in italics)
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The oral dose of morphine should be reduced by 30% to 50% to prevent any risk of overdose after the conversion, since opioids do not have complete cross-tolerance. A 33% dose reduction from the calculated dose of 100 mg is equal to 67 mg of oral morphine per day.
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[DOCX File]Date of check
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It is crucial to appreciate that conversion ratios are never more than an approximate guide (2). Patients will require frequent reassessment of efficacy and adverse effects and dose titration after patch initiation or dose change, as well as a short acting opioid for breakthrough pain (3).
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(see opioid conversion charts or seek advice from palliative care) Patches provide continuous pain relief if ongoing background pain is an issue. Patches can take 24 hours to become absorbed and the onset of pain relief is delayed.
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[DOC File]OPIOID ANALGESIA – DRUG CONVERSIONS AT KIRKWOOD …
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Examples of dose conversion: NOTE: All drug conversions are approximate and care should be taken in conversion factors, especially at higher opioid doses. Zomorph PO to Diamorphine SC: 30mg Zomorph PO BD = 60mg Zomorph PO over 24 hours ÷ 3 = 20mg Diamorphine SC over 24 hours. Zomorph PO to …
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[DOC File]Can fentanyl patches be abused
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Most published opioid conversion tables have been derived from short-term studies in opioid-naive patients, which do not account for the influence of incomplete cross-tolerance between opioids (2). A dose reduction of at least 50% is recommended when switching at high doses (e.g. morphine or equivalent doses of 1g/24 hours or more), in elderly ...
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Opioid dose conversion