Phentolamine extravasation protocol
Pathology
Alternatives: phentolamine and nitroprusside. Cocaine. Cocaine-associated chest pain ( 25% ischemia, 75% be musculoskeletal or psychological. Cocaine use may reduce the sensitivity and specificity of CK-MB and myoglobin (80(50%) for infarction. Thrombosis (increased platelet action) Vasospasm (acute)
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Vasopressor Extravasation: Dopamine, Dobutamine, Epinephrine, Norepinephrine, Phenylephrine. Antidote: Phentolamine: Reconstitute the 5mg vial of Phentolamine with 1ml of Sterile Water for Injection. Further dilute the reconstituted vial of Phentolamine with 9ml of …
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Dopamine infuse titrate per protocol. Dopamine infusion. Start at 5mg/kg/min. Adjust rate every 5min min as needed to maintain MAP of 65. Dopamine infusion. Start at 5mcg/kg/min. Titrate to MAP of 65 by adjusting rate by 1-2mcg/kg/min every 3-5min. Do not exceed 20mcg/kg/min. Dopamine infusion titrate to …
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40% of people who develop hives (uticaria) from a drug will also have swelling of deeper sub dermis which is manifested as swelling of the face/tounge/lips and may even involve th
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Hence, if blanching occurs, consideration should be given to the advisability of changing the infusion site at intervals to allow the effects of local vasoconstriction to subside. To treat extravasation, consider injecting phentolamine 5 to 10mg (diluted in 10 to 15 mL normal saline) into the site of extravasation. Phenylephrine (Neo-Synephrine)
[DOC File]SURVIVAL MANUAL - University of Michigan
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PHENTOLAMINE (REGITINE) MECHANISM OF ACTION *Alpha adrenergic blocking agent *Half life is 19 minutes. INDICATIONS *Cavrnousography *Pheocrisis *extravasation of norepinephrine injection. DOSAGE *Intra cavernosal--1 mg *Pheo crisis--1 to 5 mg. CONTRAINDICATIONS *hypersensitivity *hypotension, MI, angina, UNTOWARD EFFECTS AND TREATMENT
Extravasation - Pitt Pharmacy Portfolio
Extravasation of Intravenous Last Review Date: June 2013. Non-Chemotherapeutic Agents. Policy Number: P-IV-14. POLICY . It is the policy of UPMC Presbyterian Shadyside that the professional nurse will minimize the risk of extravasation. If extravasation occurs, the nurse will recognize and manage the extravasation according to policy. GENERAL ...
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Date Consideration Outcome October 2011 Dexrazoxane RED – To be used in strict accordance with HEFT protocols for suspected anthracycline extravasation. It must only be used as per licence and must be prescribed in the same way as any other cytotoxic drug.
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vii. Extravasation is a major concern. (a) Careful monitoring is essential. (b) Phentolamine should be available. h. Vasopressin (Pitression) i. A potent vasopressor medication recommended in ACLS protocols. ii. A naturally occurring hormone secreted in the body in response to: (a) Plasma hyperosmolality (b) Intravascular volume depletion. iii.
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In regards to vasoactive substance extravasation (e.g., dopamine and neosynephrine), plastic surgery should be consulted immediately because these injuries can become more limb threatening. Treatment begins with injection of subcutaneous phentolamine and application of topical nitroglycerin.
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