Po equivalent ceftriaxone

    • [PDF File] Pediatric IV to PO Conversion - Children's of Alabama

      https://www.childrensal.org/sites/default/files/workfiles/antimicrobial/Pediatric_IV_to_PO_Conversion_Newsletter.pdf

      o can switch from IV to PO?2Generally, pediatric patients may be switched from IV to PO antibiotics as soon as they show signs of clinical improvement, develop the ability to swallow or receive enteral feeds, have a functional gastrointestinal system or unimpaired drug absorption, and an orally bioavai.

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    • [PDF File] 2020 Antimicrobial Stewardship Program Adult Dosing …

      https://physicians.northernhealth.ca/sites/physicians/files/physician-resources/antimicrobial-stewardship/documents/antimicrobial-stewardship-guidelines.pdf

      2020 Antimicrobial Stewardship Program Adult Dosing Guidelines. 400 mg IV q24h400 mg IV q24h400 mg IV. 24h; give AD on dialysis days400 mg IV q24hPoorer tissue perfusion in obese patients. Obese patients are likely to benefit from increased doses Consider uppe. sing in severe infections (e.g. up to 400.

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    • Intravenous to Oral (IV:PO) Anti-Infective Conversion Therapy

      https://journals.sagepub.com/doi/pdf/10.1177/107327480000700211

      The term “anti-infective con-version” describes the practice of converting intravenous anti-infec-tion therapy to an alternative oral formulation. This conversion from intravenous (IV) to oral (PO) thera-py has been practiced in an uncon-trolled fashion since the earliest years of the anti-infective era. As conversion therapy was based on ...

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    • [PDF File] Antibiotics: IV to PO Stepdown - VCH

      https://aspires.vch.ca/Documents/My%20Daily%20Stewardship/IV%20to%20PO%20poster%20version.pdf

      Antibiotics: IV to PO Stepdown Recent studies support using oral antibiotics to treat many infections. If your patient is receiving IV antibiotics, consider a switch to oral if:

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    • [PDF File] ADULT ANTIMICROBIAL DOSING GUIDELINE#

      https://idmp.ucsf.edu/sites/g/files/tkssra4251/f/2022_General%20Adult%20Antibiotic%20Dosing%20Card_7x17_Antibiogram_Draft_0615.22.pdf

      Approved by the Antimicrobial Subcommittee and the Pharmacy and Therapeutics Committee June 2022 These dosing recommendations are meant as guidance for initial dose selection based on available literature and should not replace clinical judgement. Antimicrobial dosing should account for patient (weight, renal function), antimicrobial …

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    • [PDF File] Antimicrobial Stewardship Program Perspective: IV-to-PO …

      http://www.rimed.org/rimedicaljournal/2018/06/2018-06-31-antimicrobial-cunha.pdf

      nsitional antibiotic therapy,” now known as IV-to-PO switch therapy. Early experience with this therapy demonstrated that some or most antibiotic therapy in hospital could be transitioned to PO following initial IV therapy.3,4 It became clear that patients treated with IV-to-PO therapy for common infec-tious diseases, e.g., community acquired ...

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    • [PDF File] Guideline/Protocol Title: Enterobacterales Bloodstream …

      https://idmp.ucsf.edu/sites/g/files/tkssra4251/f/UCSFGNRBacteremia_09_2021_FINAL.pdf

      Dosing based on adjusted body weight (AdjBW) 60-69 kg. 1 DS PO TID. Trimethoprim-sulfamethoxazole (TMP/SMX) 8-10 mg/kg/day (doses divided into 2-3 doses) Double strength (DS) = 160/800 (TMP/SMX) Avoid use in patients who are on warfarin unless there is close monitoring plan of the INR.

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    • [PDF File] Adult IV to Oral Antibiotic Switch Therapy Guidelines

      https://www.dgeducationcentre.co.uk/wp-content/uploads/2017/07/Intravenous-to-oral-guidelines.pdf

      Adult IV to Oral Antibiotic Switch Therapy Guidelines Patients receiving IV antibiotics may be considered suitable for a switch to oral WITHIN THE FIRST 48hrs and every 24hrs thereafter IF the following inclusion criteria are MET and NONE of the specific exclusion criteria apply. The need for IV therapy should be reviewed after 24hrs however 48hrs will …

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    • SA Health Fact Sheet Template - Green on White - Helix …

      https://www.sahealth.sa.gov.au/wps/wcm/connect/86d0af8047ca4a108ca28dfc651ee2b2/IV+to+Oral+Switch+Guideline+for+Adult+Patients_Mar2015.pdf?MOD=AJPERES&CACHE=NONE

      A large number of clinical trials support the early switching to oral antimicrobials after this period of time with equal treatment efficacy and no adverse effects on patient outcome.3,8-10 The flow chart in this guideline aids the clinician in deciding if it is safe to switch a patient to oral antimicrobials.

      TAG: ceftriaxone transition to po

    • Empiric Antibiotic Guidelines for Common Infections in Adults

      https://www.bridgeporthospital.org/-/media/Files/Bridgeport/PDF/Library/2022_BH_MC_Empiric_Antibiotic_Guidelines.ashx

      Empiric Antibiotic Guidelines for Common Infections in Adults. Developed based upon published recommendations and BH/MC susceptibility data. Doses listed below are for normal renal function; pharmacists will adjust doses per renal function as per the YNHH Renal Dose Adjustment Protocol. IV antibiotics will be converted to PO equivalents when ...

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    • [PDF File] Bacterial Urinary Tract Infection (UTI) - Johns Hopkins Medicine

      https://www.hopkinsmedicine.org/-/media/antimicrobial-stewardship/bacterial_uti_guidelines.pdf

      Ciprofloxacin 500 mg PO Q12H for 7 days TMP/SMX 1 DS PO Q12H for 7-10 days Cefadroxil* 1 g PO Q12H for 14 days Cefuroxime* 500 mg PO Q12H for 14 days Oral Fosfomycin can be considered if susceptible for Gram-negative MDR organisms (susceptibilities must be requested). Consult ID Pharmacist for dosing.

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    • [PDF File] Microsoft Word - A Quick Guide to SWITCH.doc

      https://www.safetyandquality.gov.au/sites/default/files/migrated/4.3-A-Quick-Guide-to-Switch_Southern-Health.pdf

      Benefits of Early Switch to Oral Therapy. Decreased risk of complications from IV lines: thrombophlebitis, catheter related infections. More patient friendly (improves mobility and comfort) May lead to earlier discharge. Saves medical and nursing time. Reduction in costs: Direct ‐ medication Indirect – diluents, equipment, needles.

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    • [PDF File] Northern Health Physicians

      https://physicians.northernhealth.ca/sites/physicians/files/news/documents/2017/CPS-IV-to-PO.pdf

      Conversion from IV to PO antimicrobials facility as well as aim for positive clinical reduced risk of line-related infections restrictions for patients.

      TAG: ceftriaxone and zosyn coverage

    • [PDF File] Stanford De-escalation Guide for Gram-negative Bacteremia

      https://med.stanford.edu/content/dam/sm/bugsanddrugs/documents/clinicalpathways/SHC-GNR-Bacteremia-de-escalation-guide.pdf

      remia. Higher dose may be considered for deep seated infections, obese (BMI ≥ 30), high CrCl > 100 ml/min. Use clinical judgement. **Clinical reports of emergence of resistance has been reported mainly in Enterobacter spp19 Higher mutation rates reported in experimental model of E. cloacae complex, E, aerogenes, C. freundii, H. alvei than Providencia spp, …

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    • [PDF File] IV to PO Pharmacy Conversion Protocol - FormWeb

      https://formweb.com/files/fmolhs/documents/IV%20to%20PO%20conversion%20Guide.pdf

      IV to PO Pharmacy Conversion Protocol. Inclusion Criteria for IV to PO Conversion: Infections that Require IV Antibiotics. Must satisfy below criteria: Tolerate oral diet or enteral nutrition and/or receiving oral medications. Infection does not require IV antibiotics. Afebrile (< 100.4 ̊F in the last 24 hours)

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    • [PDF File] Stanford Health Care Antimicrobial Dosing Reference Guide

      https://med.stanford.edu/content/dam/sm/bugsanddrugs/documents/antimicrobial-dosing-protocols/SHC%20Antimicrobial%20Dosing%20Guide.pdf

      Draw peak 30 min after infusion ends Once daily dosing: goal peak 35 – 60 mcg/mL; goal trough < 4 mcg/mL Conventional dosing: goal peak 25 – 35 mcg/mL for serious infections; 15 – 20 mcg/mL for UTI; goal trough < 4 – 8 mcg/mL. Doses > 8 mg/kg q24h increase the risk of CPK elevations and myopathy.

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    • [PDF File] Antimicrobial Stewardship Program Empiric Treatment …

      https://physicians.northernhealth.ca/sites/physicians/files/physician-resources/antimicrobial-stewardship/documents/empiric-treatment-guidelines-common-infections.pdf

      Note: All doses contained in this document should be adjusted for renal function (refer to the Antimicrobial Stewardship Program Adult Dosing Guidelines Pocket-card [10-110-6004])

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    • [PDF File] Pediatric Empiric Antimicrobial Therapy Recommendations …

      https://www.advocatechildrenshospital.com/assets/documents/pediatric-clinical-pathways/pediatric-antimicrobial-stewardship/aah-pediatric-empiric-antimicrobial-therapy-recommendations-(8.2020).pdf

      These are general recommendations only and should not supersede clinical judgment. Patients must be evaluated individually. Appropriate alterations in therapy must be made when culture and sensitivity data are available.

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    • [PDF File] Conversion from IV to Oral Antibiotics Guidelines

      https://www.safetyandquality.gov.au/sites/default/files/migrated/4.2-Conversion-from-IV-to-Oral-Antibiotics-Guidelines_RPH.pdf

      NSIDER CONVERSION FROM IV TO ORAL ANTIBIOTIC. temperature <38°C or improving over 24 hrs. signs & symptoms improved or resolved. oral / nasogastric intake tolerated & absorbed. no diagnostic indication for IV therapy eg. endocarditis, febrile neutropenia, S. aureus bacteraemia, meningitis, osteomyelitis.

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    • [PDF File] IV to PO Antibiotic Step-Down Guidelines - University of …

      https://web.uri.edu/wp-content/uploads/sites/1349/IV-to-PO-Stepdown-2019-JD.pdf

      Candidates for Antimicrobial Step-Down therapy: Patient is able to tolerate PO medication AND has a functioning GI tract The infection is treatable with oral antimicrobial therapy AND the indications and spectrum of activity are identical or similar between alternative drugs No evidence of malabsorption, dysphagia, or gastrointestinal bleed

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