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[DOC File]National PBM Monograph Template Rev20091005
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In clinical trials, the mean pharmacokinetic parameters in healthy subjects showed a dose-proportional (IV bolus dose range of 6mg/kg-18mg/kg) increase in area under the curve (AUC) of fospropofol from 19.2± 3.59 to 50.3± 8.4, respectively.
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[DOCX File]Lippincott Williams & Wilkins
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Subgroup analysis for trials with propofol bolus regimens in both PCS and CCS groups. Figure K. Risk of oxygen desaturation. Subgroup analysis for trials with local or locoregional anesthesia. Figure L. Risk of rescue intervention for adverse events. Subgroup analysis for trials with local or locoregional anesthesia. Figure M. Total propofol dose.
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[DOC File]Propofol Dosing Guidelines - Stanford University
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D. Titrate the propofol infusion rate, not the ketamine infusion rate. If the patient seems to require a lot of propofol, give 25-50 µg fentanyl boluses. F. As with propofol, the ketamine infusion rate was designed for adults of average weight (60-80 kg). Adjust upward or downward for larger or smaller patients.
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[DOC File]A Comparative Study of Ketamine Associated to Target ...
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When the dose of 2-2.5 /ml. of propofol was reached 0.5 mg./kg. of ketamine was injected as an IV bolus. In cases of large volume surgeries an additional dose of 25-50 mg. of ketamine was administered. Recovery time ranged between 1-4 min. (mean 2 min.10 seconds).
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[DOC File]The Use Of Target Controlled Infusion (TCI) System With ...
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The routine procedure was: premedication with Midazolam (3mg), Meperol (50 mg.) in IV bolus, TCI Propofol induction dose: 3.60 g/ml, maintenance doses: 2.07 g/ml. Recovery time: 2 min.13 seconds. Local anesthesia was performed with lidocaine (1 to 0.12 %) with epinephrine. The endpoint of this study included: TCI Propofol dose required ...
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Anesthesiologists typically use an approximately 1 mg/kg bolus in the OR to induce general anesthesia prior to intubation, and this dose frequently causes immediate hypotension – unless you are prepared to immediately correct with pressors, DO NOT DO BOLUS Propofol even though it is the recommended dosing in many status algorithms.
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Propofol bolus dose