Propofol infusion related syndrome
[DOC File]ICU SEDATION GUIDELINES
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- Propofol infusion syndrome– r/t phenol portion – affect mitochondria Occurs w/ prolonged high dose infusion (>75 mcg/kg/min >24H) Abnormal lipid metabolism in …
[DOC File]QMC Adult Critical Care Induction Manual for Junior ...
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Propofol. Benzodiazepines. ... depend on the type of trauma related to the surgical procedure that is being performed. ... Propofol infusion syndrome – green urine/hair. Not used in pregnancy/delivery. Not commonly used in paediatrics – unproved safety profile. Thiopentone.
[DOCX File]Home Page: British Journal of Anaesthesia
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The largest series describing propofol infusion syndrome reports that it occurs at doses greater than 83 mcg/kg/minute for greater than 24 hours (35). This is well above the usual clinical dose, even for TBI. High-dose propofol should, therefore, be utilized with caution.
[DOC File]Propofol Dosing Guidelines
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little evaluation of propofol infusion syndrome with potential risk of a large-scale change to much greater propofol use. Given modest benefits of propofol in meta-analysis and their questionable clinical significance, a small increase in PRIS would reverse potential propofol …
[DOCX File]Research Projects - University of Virginia
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Imam TH. Propofol-related infusion syndrome: role of propofol in medical complications of sedated critical care patients. Perm J. 2013; 17: 85–7 . 99. Agrawal N, Rao S, Nair R. A death associated with possible propofol infusion syndrome. Indian J Surg. 2013; 75: 407–8 . 100. Diaz JH, Roberts CA, Oliver JJ, Kaye AD.
[DOCX File]Explanations
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Evaluation of a clinical decision support (CDS) tool to aid in the prevention of propofol infusion syndrome (PRIS) Nate Hedrick. The prevalence of characteristic symptoms of propofol-related infusion syndrome (PRIS) in patients treated with valproic acid. Hasan Kazmi.
[DOCX File]www.hsrsna.com
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Propofol Infusion Syndrome ( CHECK Triglycerides after 48 hours use), green urine MIDAZOLAM P 50mg in 50 ml NaCl or 100mg in 50 ml NaCl A 0 – 10 ml/hr I SEDATION CO-INDUCTION SEIZURE CONTROL M Benzodiazepine; Enhance actions of GABA and GABA-A receptors, leading to neuronal inhibition S Retrograde amnesia, Delirium ,Respiratory …
[DOCX File]NYSPFP
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D. Titrate the propofol infusion rate, not the ketamine infusion rate. If the patient seems to require a lot of propofol, give 25-50 µg fentanyl boluses. F. As with propofol, the ketamine infusion rate was designed for adults of average weight (60-80 kg). Adjust upward or downward for larger or smaller patients.
Propofol-Related Infusion Syndrome
Propofol related infusion syndrome (PRIS) is characterized by metabolic acidosis, hypotension, bradyarrhythmias, lipemia, rhabdomyolysis, and cardiac failure. If suspect PRIS, propofol should be stopped immediately and an alternative sedative agent be utilized.
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