Propofol infusion syndrome treatment
[DOC File]ICU SEDATION GUIDELINES
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Propofol Infusion Syndrome ( CHECK Triglycerides after 48 hours use), green urine MIDAZOLAM P 50mg in 50 ml NaCl or 100mg in 50 ml NaCl A 0 – 10 ml/hr I SEDATION CO-INDUCTION SEIZURE CONTROL M Benzodiazepine; Enhance actions of GABA and GABA-A receptors, leading to neuronal inhibition S Retrograde amnesia, Delirium ,Respiratory …
[DOCX File]Explanations
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Lewejohann J C, Hansen M, Zimmermann C, Muhl E, Bruch H P. Propofol infusion syndrome in a patient with severe multiple trauma. European Society of Intensive Care Medicine, 17th Annual Congress. Berlin,Germany, 10-13 October 2004.
[DOCX File]Home Page: British Journal of Anaesthesia
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Evaluation of a clinical decision support (CDS) tool to aid in the prevention of propofol infusion syndrome (PRIS) Nate Hedrick The prevalence of characteristic symptoms of propofol-related infusion syndrome (PRIS) in patients treated with valproic acid
[DOCX File]www.hsrsna.com
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Average cost $3.54 (20mg/day) Propofol 48 hr) Average cost $22.8/24 hr (@ 30mcg/kg/min) Dexmedetomidine --- 2.5-4 hr 2-4 hr Possess analgesic sparing effect; potential anxiolytic and anti-shivering effect
[DOC File]QMC Adult Critical Care Induction Manual for Junior ...
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Contraindicated for the treatment of perioperative pain in coronary artery bypass graft surgery. Gabapentin Side effects: (common) sedation, confusion, dizziness, ataxia. Adjust dosing in renal failure pts. Abrupt discontinuation associated with drug withdrawal syndrome, seizures.
wiki.med.umich.edu
High dose propofol (> 50 mcg/kg/minute for > 48 hours) may cause propofol infusion syndrome. Propofol related infusion syndrome (PRIS) is characterized by metabolic acidosis, hypotension, bradyarrhythmias, lipemia, rhabdomyolysis, and cardiac failure. If suspect PRIS, propofol should be stopped immediately and an alternative sedative agent be ...
[DOCX File]NYSPFP
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The largest series describing propofol infusion syndrome reports that it occurs at doses greater than 83 mcg/kg/minute for greater than 24 hours (35). This is well above the usual clinical dose, even for TBI. High-dose propofol should, therefore, be utilized with caution.
Propofol Infusion Syndrome in Children — Pediatric EM Morsels %
NOTE: Propofol infusion syndrome is a very rare complication that has been reported in the status literature, likely due to the common practice of using extremely high propofol doses for prolonged periods in these patients.
[DOCX File]Research Projects - University of Virginia
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- Propofol infusion syndrome– r/t phenol portion – affect mitochondria Occurs w/ prolonged high dose infusion (>75 mcg/kg/min >24H) Abnormal lipid metabolism in …
[DOC File]ICU SEDATION GUIDELINES
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little evaluation of propofol infusion syndrome with potential risk of a large-scale change to much greater propofol use. Given modest benefits of propofol in meta-analysis and their questionable clinical significance, a small increase in PRIS would reverse potential propofol …
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