Propofol related infusion syndrome
Propofol-Related Infusion Syndrome
Propofol related infusion syndrome (PRIS) is characterized by metabolic acidosis, hypotension, bradyarrhythmias, lipemia, rhabdomyolysis, and cardiac failure. If suspect PRIS, propofol should be stopped immediately and an alternative sedative agent be utilized.
[DOC File]Propofol Dosing Guidelines - Stanford University
https://info.5y1.org/propofol-related-infusion-syndrome_1_930dbb.html
Evaluation of a clinical decision support (CDS) tool to aid in the prevention of propofol infusion syndrome (PRIS) Nate Hedrick. The prevalence of characteristic symptoms of propofol-related infusion syndrome (PRIS) in patients treated with valproic acid. Hasan Kazmi.
[DOCX File]Research Projects - University of Virginia
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Or high cardiac output? or high output failure? or propofol infusion syndrome? or propofol related infusion syndrome?).mp. Fosinopril/ or Lisinopril/ or Perindopril/ or Enalapril/ or Captopril/ or Quinapril/ or (Accupril or Accuprin or Accupro or Accupron or Ace-bloc or Acenorm or Acenor-m or Aceon or Acepress or Acepril or Aceprilex or Acequin ...
[DOCX File]NYSPFP
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little evaluation of propofol infusion syndrome with potential risk of a large-scale change to much greater propofol use. Given modest benefits of propofol in meta-analysis and their questionable clinical significance, a small increase in PRIS would reverse potential propofol …
[DOC File]ICU SEDATION GUIDELINES
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- Propofol infusion syndrome– r/t phenol portion – affect mitochondria Occurs w/ prolonged high dose infusion (>75 mcg/kg/min >24H) Abnormal lipid metabolism in …
[DOC File]Lippincott Williams & Wilkins
https://info.5y1.org/propofol-related-infusion-syndrome_1_3006f1.html
The largest series describing propofol infusion syndrome reports that it occurs at doses greater than 83 mcg/kg/minute for greater than 24 hours (35). This is well above the usual clinical dose, even for TBI. High-dose propofol should, therefore, be utilized with caution.
[DOCX File]Explanations - Lippincott Williams & Wilkins
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D. Titrate the propofol infusion rate, not the ketamine infusion rate. If the patient seems to require a lot of propofol, give 25-50 µg fentanyl boluses. F. As with propofol, the ketamine infusion rate was designed for adults of average weight (60-80 kg). Adjust upward or downward for larger or smaller patients.
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