Pulmonary hypertension severe end stage

    • [PDF File]Severe pulmonary hypertension in patients with severe ...

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      Severe pulmonary hypertension (PHT) in patients with severe aortic valve stenosis (AS) is not uncommon, with a reported prevalence as high as 29% among patients having an invasive hemodynamic study before aortic valve replace-ment (AVR) (1). Pulmonary hypertension also has been associated with end-stage AS, sudden clinical deterioration,

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    • [PDF File]PULMONARY ARTERIAL HYPERTENSION Copyright © 2018 …

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      PULMONARY ARTERIAL HYPERTENSION PPAR agonist pioglitazone reverses pulmonary ... We recapitulated our major pathogenic findings in human end-stage PAH: (i) in the pressure-overloaded failing RV (miR-197 and miR-146b up-regulated), (ii) in peripheral pulmonary arteries (miR-146b up- regulated, miR-133b ... To model severe PAH and RV failure (fig ...

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    • [PDF File]Right ventricular assist device in end-stage pulmonary ...

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      Right ventricular assist device in end-stage pulmonary arterial hypertension: insights from a computational model of the cardiovascular system Lynn Punnoosea,⁎, Daniel Burkhoffb, Stuart Richc, Evelyn M. Horna aDivision of Cardiology, Weill Cornell Medical College, New York, NY bDivision of Cardiology, Columbia University College of Physicians and Surgeons, New York, NY

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    • [PDF File]Screening for pulmonary arterial hypertension in systemic ...

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      ABSTRACT Pulmonary arterial hypertension (PAH) is a dreaded complication of systemic sclerosis (SSc) that occurs in ∼10% of patients. Most individuals present with severe symptoms, significant functional impairment and severe haemodynamics at diagnosis, and survival after PAH diagnosis is poor.

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    • Pulmonary hypertension in patients with chronic and end ...

      Pulmonary hypertension in patients with chronic and end-stage kidney disease Meghan E. Sise1, Andrew M. Courtwright2 and Richard N. Channick3 1Division of Nephrology, Department of Medicine, Columbia University Medical Center, New York, New York, USA; 2Massachusetts General Hospital, Institute for Patient Care, Boston, Massachusetts, USA and 3Division of Pulmonary Critical Care, Department of

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    • [PDF File]Reversal of severe pulmonary hypertension with blockade in ...

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      Reversal of severe pulmonary hypertension with â blockade in a patient with end stage left ventricular failure J G Crilley, J H Dark, J A Hall Abstract A 52 year old man with severe chronic left ventricular failure (New York Heart As-sociation class IV) was considered unsuit-able for cardiac transplantation because of

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