Relationship of dopamine to schizophrenia
[DOC File]Schizophrenia - Psychwinter's Blog
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Hasenkemp W, Kelley M, Egan G, Green A, Wilcox L, Boshoven W, Lewison B, Duncan E. Lack of relationship between acoustic startle and cognitive variables in schizophrenia and control subjects. Psychiatry Res, 187(3):324-328, 2011. PMID: 21397338; PMC3078961
[DOCX File]van Kammen DP, Kelley M. Dopamine and norepinephrine ...
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In either case, schizophrenia is believed to occur as a result of over-activity in parts of the brain controlled by dopamine. Interest in the neurotransmitter dopamine arose when it was found that neuroleptic, antipsychotic drugs, which work by inhibiting dopamine activity, can reduce the symptoms of schizophrenia.
[DOC File]Biological explanations of schizophrenia
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The dopamine hypothesis of schizophrenia formulated in the sixties states that the symptoms of schizophrenia depend upon the overactivity of the dopaminergic system (Carlsson et al., 1963). The latter would be related to an increased density of dopamine D2 receptors.
[DOC File]10-30-07 Schizophrenia
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Neuroleptic drugs (Phenothiazines) that block dopamine seem to reduce the symptoms of schizophrenia; this mainly has the most effect on positive symptoms. Further evidence is from individuals who take hallucogenic drugs, as the experience is …
[DOC File]Treatment of Schizophrenia
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Research suggests schizophrenia may be caused by a change in the level of two neurotransmitters: dopamine and serotonin. Some studies indicate an imbalance between the two may be the basis of the problem.
What is the role of dopamine in schizophrenia?
Schizophrenia Pathophysiology . Dopamine – increased dopamine activity in schizophrenia, affect many CNS pathways in brain. Subcortex – increased dopamine activity ( positive symptoms. Prefrontal – decreased dopamine activity ( negative symptoms. Evidence – increased dopamine receptors at autopsy, dopamine agonists worsen psychosis & vice-versa
[DOC File]Schizophrenia, Sleep and Antipsychotics
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Dopamine is one of the many neurotransmitters operating in the brain. Schizophrenics are thought to have an abnormally high number of D2 receptors on their receiving neurons, resulting in more dopamine binding and therefore more neurons firing.
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