Schizophrenia dopamine receptors
[DOC File]10-30-07 Schizophrenia
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Schizophrenia Pathophysiology . Dopamine – increased dopamine activity in schizophrenia, affect many CNS pathways in brain. Subcortex – increased dopamine activity ( positive symptoms. Prefrontal – decreased dopamine activity ( negative symptoms. Evidence – increased dopamine receptors at autopsy, dopamine agonists worsen psychosis ...
[DOC File]The ‘Dopamine Hypothesis’ suggests that schizophrenia ...
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The ‘Dopamine Hypothesis’ suggests that schizophrenia results from over-activity in the brain dopamine systems. Owen et al. (1978) found increased levels of dopamine and a relative excess of dopamine receptors in the brain tissue of schizophrenic patients.
[DOC File]Schizophrenia, Sleep and Antipsychotics
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The dopamine hypothesis of schizophrenia formulated in the sixties states that the symptoms of schizophrenia depend upon the overactivity of the dopaminergic system (Carlsson et al., 1963). The latter would be related to an increased density of dopamine D2 receptors.
[DOC File]Schizophrenia - Mercer University
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Distinguish key symptoms of schizophrenia. Analyze the prevailing biologic, psychological, and social theories that are the basis for understanding schizophrenia. ... Role of Other Dopamine Pathways. Role of Other Receptors. Psychological Theories. Social Theories. Interdisciplinary Treatment. Priority Care Issues. Family Response to Disorder.
[DOCX File]Psychology: Clinical – Content (AJW)
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The original version of the dopamine hypothesis suggested that an ..... of dopamine activity may be responsible for schizophrenic symptoms, (hyperdominergia) in sub-cortical regions, e.g. the limbic system (Carlsson and Lindqvit, 1963) but an updated version (Davis, 1991) suggested that although there may be an excess of dopaminergic activity in some brain regions, schizophrenia is also ...
[DOC File]Types of Signal Transmission - UCSD Cognitive Science
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The dopamine system is overactive in patients with schizophrenia. Dopamine can be converted to norepinephrine, which can be converted to epinephrine. Norepinephrine causes the fight-or-flight response, while epinephrine has the opposite effect.
[DOC File]Biological explanations of schizophrenia
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It is thought that some of the symptoms of schizophrenia are a result either of an excess of dopamine in the brain or of a super-sensitivity of the dopamine receptors. In either case, schizophrenia is believed to occur as a result of over-activity in parts of the brain controlled by dopamine. Interest in the neurotransmitter dopamine arose when ...
[DOC File]STRENGTHS AND WEAKNESS OF THE DOPAMINE HYPOTHESIS
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PET scans allow us study how dopamine works in living patients. Excess of dopamine in the mesolimbic pathway seems to be most relevant in understanding schizophrenia Amphetamines produce positive symptoms There are different types of dopamine receptors in different areas of the brain
[DOC File]Psychotic Disorders
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The downregulation of D1 receptors in the frontal cortex may contribute to the hypoactivity of the mesocortical dopamine system and thus the negative symptoms of schizophrenia. In schizophrenics, there is a correlation between fewer cortical D1 receptors with the severity of negative symptoms and with poor function in frontal executive tasks.
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