Scleroderma and lupus overlap

    • [PDF File]polymyositis-scleroderma overlap.

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      Although the overlap syndrome was defined solely on clinical criteria, only two patients were simultaneously classified in the MCTDgroup: of26 patients with overlap syndrome, 13 were negative for anti-RNPantibodiesandamong13 withanti-RNPantibodies, 11 had additional precipitating antibodies. 56 control sera were obtained from healthy volunteers ...


    • [PDF File]The progressive systemic sclerosis/systemic lupus overlap ... - …

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      A specific overlap termed mixed connective tissue disease is one such condition.' Others are simply termed undif-ferentiated connective tissue disease.2 Sjogren's syndrome, fibrosing alveolitis, and Raynaud's phenomenon may accompany all of the above but may also exist on their own as 'primary' conditions. The association of lupus and scleroderma


    • [PDF File]Systemic Sclerosis-Polymyositis Overlap Syndrome Associated …

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      Overlap syndromes aggravate the clinical course of the disease and raise treatment controversies. Scleroderma-AIH is a rare overlap syndrome, predominantly associated with the limited subtype of SSc, yet not to be disregarded as a feature of gastrointestinal involvement in patients with diffuse SSc. Patients with SSc and persistent elevation


    • [PDF File]MIXED CONNECTIVE TISSUE DISORDERS (MCTD)

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      Overlap syndrome: The term has been used when two or more autoimmune diseases occur in the same individual simultaneously . Example: Systemic lupus erythematosus, rheumatoid arthritis, scleroderma, dermatomyositis, polymyositis in various combinations. MIXED CONNECTIVE TISSUE DISORDERS (MCTD) DEFINITION MCTD was first described b: y Sharp et al ...


    • [PDF File]Systemic sclerosis (scleroderma) - Orphanet

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      • Localized scleroderma (morphea, linear scleroderma with atrophy of the affected extremity, "en coup de sable" with and without facial hemiatrophy). • Scleroderma - like skin changes o UCTD o Eosinophilic fasciitis with eosinophilia o Eosinophilia myalgia syndrome o Overlap syndromes (scleroderma, with SLE, or SS, or DM/PM, or RA)


    • [PDF File]Do A

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      discoid lupus erythematosus (DLE) and localized scleroderma within the same lesions. Based on our case and other reported cases in the literature, the following features are common in patients with an overlap of lupus erythematosus (LE) and local-ized scleroderma: predilection for young women, photodistributed lesions, DLE, linear morphology


    • [PDF File]Systemic Lupus Erythematosus and Overlapping

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      Systemic Lupus Erythematosus and Overlapping “Connective Tissue Diseases” Kathleen M. O’Neil, MD Professor of Pediatrics and Chief Division of Pediatric Rheumatology Indiana University School of Medicine James Whitcomb Riley Hospital. SLE: A Complex Inflammatory Disease with Autoimmunity •Named for the wolf in Latin, lupus often involves the skin –and so much more •4 skin & membrane …


    • [PDF File]Undifferentiated Connective Tissue Disease and Overlap ... - …

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      Overlap Syndromes Rheumatoid arthritis, myositis, scleroderma and Sjogren’s syndrome all have some symptoms in common and can coexist with lupus or a lupus-like syndrome. With time some patients can evolve to develop more classical disease processes and become a “textbook” case, other continue in a overlap state forever.


    • [PDF File]Sudden Renal Failure in a Scleroderma Patient: A Clinical ...

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      Such overlap of scleroderma with lupus is very rarely reported. Introduction S cleroderma is a multi-systemic connective tissue disorder which can cause acute renal failure. The condition is called scleroderma renal crisis and it often has a poor prognosis. 1 Thus, development of renal failure in a patient of scleroderma is often an adverse prognostic marker and requires immediate management. …


    • [PDF File]Overlap Syndrome - Lupus Foundation of America

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      Overlap Syndrome •Patients with overlap syndrome can have features of systemic lupus erythematosus, systemic sclerosis, polymyositis, or dermatomyositis, with rheumatoid arthritis and Sjögren's syndrome evolving concurrently or consecutively during the course of the disease


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