Severe mitral valve regurgitation prognosis
[PDF File]fining Severe Secondary Mitral Regurgitation
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n severe primary mitral regurgitation (MR),“it is the abnormal valve that makes the heart sick” (1). Surgical correction of primary MR, ideally by mitral valve repair, corrects left ventricular (LV) vol-ume overload, allowing a normal lifespan (2–4). Conversely, secondary or functional MR is caused by
[PDF File]Mitral Regurgitation: Causes, Natural History, Classic and ...
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to severe MR1 • Of those referred 49% most are denied surgery due to age, comorbidities and LV dysfunction2 Epidemiology of Mitral Regurgitation 1Nkomo VT et al. Lancet 2006; 368:1004-11 2Mirabel M et al. Eur Heart J 2007;28:1358-65 Prevalence of Mitral valve disease by age Population based clinical trials Olmsted County Mitral Mitral Aortic ...
[PDF File]MITRAL REGURGITATION - Canadian Cardiovascular Society
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- Severe MR associated to poor prognosis - 20% MR after ACS – more adverse outcomes PATHOPHYSIOLOGY o 50% regurgitant volume is ejected in LA before aortic valve opening o Orifice size and pressure gradient are labile – gradient depends on SVR and mitral annulus o Severe MR – LV volume overload (! preload and afterload)
Mitral regurgitation
reduced contraction, mitral valve tenting affects leafletcoaptation and causes functional MR. Degenerative (organic) MR involves mitral valve prolapse or,less frequently,calcificationsof the mitral annulus. Mitral valve prolapse is an abnormal systolic valve movement of one or both of the mitral leaf-lets towards the left atrium (≥2 mm beyond the
[PDF File]Evolution of Functional Mitral Regurgitation and Prognosis ...
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of the following: a history of surgical mitral valve treatment or presence of severe degenerative mitral valve disease (n ¼ 11), incomplete echocardiogram data (n ¼ 8), and a follow-up period of
[PDF File]Contemporary Management of Chronic Severe Mitral …
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Outcomes in patients with untreated severe chronic mitral regurgitation One year survival was 96.3 + 1.3 % in operated patients vs. 88.2 + 2.5 % in the non-operated patients (p=0.003)1 Patients with primary mitral regurgitation have an excess mortality rate of 6.3% per year2 Within 10-years, the incidence of atrial fibrillation is ~30% and incidence of clinical heart failure
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