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[DOCX File]Title: Statin Induced Autoimmune Myopathy
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The mechanism of statin-induced myopathy is unknown but one possible mechanism suggested is due to mitochondrial dysfunction caused by reduced intramuscular coenzyme Q10 (9). Coenzyme Q10 (CoQ10), also known as ubiquinone, is a fat-soluble antioxidant found in all cell types throughout the body (10, 11).
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[DOCX File]University of Manchester
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However, like the statin-fibrate combination, there is a lack of health outcome evidence demonstrating a greater benefit of these combinations versus a statin alone. If the statin-fibrate combination is selected, the lowest effective statin dose should be used when combined with gemfibrozil or fenofibrate.
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[DOC File]Pharmacology: Basics for RNs
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A Quick Summary of Key Rheumatic Diseases [Bracketed numbers refer to linked MKSAP Board Review questions] Osteoarthritis Rx [3, 8, 13, 37] Initial Rx 2cd 3rd 4th Tylenol
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[DOC File]WATER DEPRIVATION TEST AND DESMOPRESSIN TEST IN …
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Inclusion Body Myositis. Statin Myopathy. Vasculitis has been associated with all the following except: Amphetamine use. Polyarteritis nodosa. Rheumatoid . Wegener’s granulomatosis. Polymyalgia rheumatica. The following are true in GBS electrophysiological studies except. Slowing of peripheral conduction velocity. Increased central conduction ...
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[DOC File]SPS
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The patient has the features of a statin-induced immune-mediated necrotizing myopathy (IMNM), recently described as being associated with the anti-HMGCR antibody. First-line immunotherapy with glucocorticoids is appropriate while further investigations are undertaken, although many cases of IMNM ultimately require more aggressive immunotherapy.
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[DOC File]curriculum vitae updated may, 1996
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Jan 01, 2015 · The term “Drug-induced hypertension” is high blood pressure that results from a chemical substance or a drug [129]. ... Drugs belonging to the statin category have been utilized in several large clinical trials to prevent strokes and heart attack and extend survival among patients having atherosclerosis [152]. ... Myositis (inflammation of ...
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[DOC File]STATIN-FIBRATE REPORT: Focus on Safety
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Monitor INR prior to commencing a statin, fibrate or Omacor and around the time of dose adjustments. If prescribing drugs which may also induce or inhibit cytochrome P450 3A4 increased INR monitoring or statin withdrawal is needed. References. 1 Statin induced myopathy (Clinical Review). BMJ 2008; 337: 1159-1162
statin induced myopathy

[DOC File]Pharmacy Benefits Management Services Home
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Curriculum Vitae. Paul S Phillips, MD. Office: San Diego Heart & Vascular. 501 Washington Street, Ste 512. San Diego, CA 92103. Last Updated 2-14-11
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[DOC File]Neuromuscular Questions
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Table 11. Statin Utilization (August-October 2011) Statin (All doses combined) Unique Patients Pitavastatin 28 Lovastatin 34,703 Simvastatin 1,172,010 Pravastatin 156,793 Atorvastatin 16,435 Fluvastatin 917 Fluvastatin XL 633 Rosuvastatin 292,522 Pharmacoeconomic Analysis
statin induced polymyositis

Statin use is associated with myositis | The Myositis Association
However, although these factors have been associated with statin-induced myopathy, their association with statin-induced autoimmune myositis remains unclear. Epidemiology: Autoimmune myositis is rare, with an estimated prevalence of 22 in 100,000 (20) and statin-induced autoimmune myositis is rarer still, with a prevalence of 1 in 100,000 (21).
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Statin induced myositis