Statin with lowest risk of myalgia
[DOC File]STATIN-FIBRATE REPORT: Focus on Safety
https://info.5y1.org/statin-with-lowest-risk-of-myalgia_1_b26651.html
If the statin-fibrate combination is selected, the lowest effective statin dose should be used when combined with gemfibrozil or fenofibrate. d) Providers choosing to prescribe statin-fibrate therapy, regardless of specific statin or fibrate used, should discuss the …
[DOCX File]spiral.imperial.ac.uk
https://info.5y1.org/statin-with-lowest-risk-of-myalgia_1_d33bd5.html
No differences in myalgia or other pain measures were observed in a randomized re-challenge trial with 3 statin/placebo paired cross-over comparisons among 8 patients with prior statin-related myalgia (with or without CK elevations), and 5 of the patients resumed statin therapy.248In another trial, 86 patients were assigned simvastatin 40 mg ...
[DOC File]Product Information for Ezetrol (ezetimibe)
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The greatest LDL-C reducing effect is seen with the lowest dose of each statin, with only a further 2-9% incremental reduction in LDL-C with each doubling of the dose. Comparatively, adding 10mg of EZETROL to a given dose of a statin is shown to achieve a greater reduction in LDL-C than that achieved with statin dose doubling.
[DOC File]Pharmacy Benefits Management Services Home
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Baseline levels of CPK are not necessary unless the patient is at risk for myopathy (e.g. renal or hepatic dysfunction; concomitant drug interaction that inhibits statin metabolism, etc.). Routine monitoring of CPK is not necessary unless patient becomes symptomatic (e.g. intolerable muscle symptoms).
NATIONAL INSTITUTE FOR CLINICAL EXCELLENCE
Rash and hypersensitivity reactions have been reported but are rare. Muscle effects (myalgia, myositis and myopathy) have also been reported with the use of statins. Severe muscle damage (rhabdomyolysis) is a very rare but significant side effect. ... to £31,000 in the lowest risk group (95% CI £23,000 to £43,000). ... the Committee ...
[DOC File]OVERVIEW
https://info.5y1.org/statin-with-lowest-risk-of-myalgia_1_e39d4f.html
Myalgia is also a common adverse effect experienced by individuals taking statin medications to lower cholesterol. Some evidence suggests that individuals with low vitamin D levels may be more likely to experience myalgia, and that increasing vitamin D levels may resolve statin induced myalgia in a large percentage of patients.
[DOC File]UKMi Q&A xx
https://info.5y1.org/statin-with-lowest-risk-of-myalgia_1_190ae6.html
If co-prescription with a drug that increases systemic exposure to statins is unavoidable, it is particularly important to start on the lowest statin dose. Any patient who is given a statin concomitantly with a macrolide antibiotic, such as erythromycin or clarithromycin, should be warned to be alert for any signs of myopathy (i.e. unexplained ...
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