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NATIONAL INSTITUTE FOR CLINICAL EXCELLENCE
Statins are generally well tolerated with the most common side-effects being hepatic toxicity and muscle toxicity including myopathy, myalgia and rhabdomyolysis. Renal impairment may be a pre-disposing factor for rhabdomyolysis and the manufacturer of atorvastatin recommends creatinine kinase should be measured before starting treatment and ...
statin with least myalgia

[DOC File]Cholesterol - Hormone Restoration
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The most commonly prescribed treatments for cholesterol are the statins (HMGCoA Reductase inhibitors) which inhibit endogenous production of LDL Cholesterol and also up regulate its uptake by the liver. ... except high risk groups or myalgia) Only if myalgia or high risk INR ... If CK less than 5 x ULN, continue medication if muscle related ...
statins and myalgias

CoQ10 and L-Carnitine for Statin Myalgia
Appendix 1. ACC/AHA/NHLBI Definitions of Muscle Toxicity Associated with Statins or Fibrates (Definitions vary between studies and are not always consistent in their terminology. In most studies, definitions of terms used for describing muscle symptoms are not provided.) 79 . Myalgia: Muscle aches or weakness without CK elevation
symptoms of myalgia from statins

[DOC File]STATIN-FIBRATE REPORT: Focus on Safety
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Nov 12, 2013 · Although the risk for serious adverse events related to statins is low, other less severe adverse events such as muscle complaints (e.g., myalgias) occur more commonly with higher intensity statins and may lead to decreased adherence and reluctance to continue statin therapy.
statin with lowest risk of myalgia

UKMi Q&A xx - SPS
BACKGROUND: Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) are widely used for the treatment of hypercholesterolemia and coronary heart disease and for the prevention of stroke. There have been various adverse effects, most commonly affecting muscle and ranging from myalgia …
statin myalgia chart

[DOCX File]Title: Statin Induced Autoimmune Myopathy
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Statins for the prevention of cardiovascular events ... diarrhoea, nausea and vomiting). Rash and hypersensitivity reactions have been reported but are rare. Muscle effects (myalgia, myositis and myopathy) have also been reported with the use of statins. ... the cost per LYG ranged from less than £1000 to £121,000 and varied according to ...
statin myalgia comparison

[DOC File]SPS
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: Autoimmune myositis is rare, with an estimated prevalence of 22 in 100,000 (20) and statin-induced autoimmune myositis is rarer still, with a prevalence of 1 in 100,000 (21). There is less of a female preponderance in statin-induced autoimmune myositis (20), and onset appears to …
statin induced myalgia

[DOCX File]Pharmacy Benefits Management Services Home
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Should patients on statins take Coenzyme Q10 supplementation to reduce the risk of statin ... (n=70 or less) and of relatively short duration (16). ... or a statin and matched placebo (n=10). Patients were stratified by history of statin related myalgia. Details of the specific statin (and dose) being used by each patient were not available ...
statin least likely to cause muscle pain

[DOC File]WATER DEPRIVATION TEST AND DESMOPRESSIN TEST IN …
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The absolute risk of incident diabetes is small, and therefore, the benefits of statins outweigh the risk (NICE 2016). It is noteworthy that women (Mora et al 2010) and the elderly (Chogtu et al 2015) are more at risk. High dose and high intensity statins are linked to diabetes onset, when compared with a …
statin with least myalgia

Statins with less myalgia