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[DOC File]OECD.org - OECD
https://info.5y1.org/sub-chronic-toxicity_1_cd7389.html
The data derived from subchronic inhalation toxicity studies can be used for quantitative risk assessments and for the selection of concentrations for chronic studies. Definitions used in the context of this Guideline can be found in Annex 1 and in GD 39.
chronic vs subchronic

[DOC File]STUDY PROFILE - US EPA
https://info.5y1.org/sub-chronic-toxicity_1_987c41.html
SUB-CHRONIC ORAL TOXICITY TESTING IN LABORATORY ANIMALS. Introduction. Objective of the Guidance. In the assessment and evaluation of potential toxic characteristics of feed substances, sub chronic toxicity studies in rodents are typically carried out for a period of 90 days (3 months).
subchronic schizophrenia definition

[DOCX File]United States Environmental Protection Agency | US EPA
https://info.5y1.org/sub-chronic-toxicity_1_4664ff.html
- a short-term toxicity study does not need to be conducted because a reliable sub-chronic (90 days) or chronic toxicity study is available, conducted with an appropriate species, dosage, solvent and route of administration - [study scientifically not necessary / other information available]- a short-term toxicity study does not need to be ...
define subchronic

[DOCX File]MassDEP BWSC Regulatory Reform Initiatives
https://info.5y1.org/sub-chronic-toxicity_1_d99423.html
Need for studies depend on the nature of the drug and the phase of human investigation, including acute, sub-acute and chronic toxicity tests, tests on reproduction and fetal effects, any special toxicity tests unique to the product’s use (e.g., dermal, inhalation, etc.) and any necessary in vitro tests.
chronic toxicity vs acute toxicity

[DOC File]OECD GUIDELINE FOR THE TESTING OF CHEMICALS
https://info.5y1.org/sub-chronic-toxicity_1_912f73.html
The recommended subchronic toxicity value is set at the subchronic value from which the chronic value is derived. (The IRIS chronic RfD for cyanide incorporates an uncertainty factor 10 for subchronic-to-chronic extrapolation. The IRIS chronic RfC incorporates an uncertainty factor of 100.5 for subchronic-to-chronic extrapolation)
chronic toxicity test

Definition of Toxicity
Title: Subchronic Toxicity Study Review Created Date: 1/2/2004 1:35:00 PM Other titles: Subchronic Toxicity Study Review
chronic vs acute toxicity

[DOCX File]Acute and Sub-Chronic Studies of Ethylacetate Leaf Extract
https://info.5y1.org/sub-chronic-toxicity_1_4eae0f.html
Experiment 2: (Long term exposure or sub chronic intoxication) In this experiment 80 tilapia used where 40 of which were kept as control in 4 glass aquaria and the other fishes were divided into 4 subgroups in 4 glass aquaria containing 1/10 LC50 (3.6 mg/L) of nickel cholride for 8 weeks.
acute and chronic toxicity examples

[DOC File]www.ifif.org
https://info.5y1.org/sub-chronic-toxicity_1_9be727.html
The sub-chronic toxicity (OECD 407) test was examined using albino rats by daily oral administration of MVEA (312, 625 and 1250 mg/kg) for 28 days during which mortality, toxicity symptoms, feed consumption and body weights were monitored. Subsequently, organ weights, haematological, biochemical and histological parameters were assessed. ...
subacute subchronic toxicity

Subchronic Toxicity Study Review
1. Clinical signs of toxicity - [include cageside observations and clinical examinations; note when signs were first observed] 2. Mortality - 3. Neurological Evaluations - B. BODY WEIGHT AND WEIGHT GAIN: [include a table of body weight gain, especially 0-30, 30-60, 60-90 days, only when there is a treatment related effect] TABLE 2.
chronic vs subchronic

[DOC File]EXPERIMENTAL STUDIES ON NICKEL TOXICITY IN NILE TILAPIA
https://info.5y1.org/sub-chronic-toxicity_1_ec794c.html
"Chronic" values were not obtained for oxamyl and pirimicarb. Ratios of acute toxicity to subchronic toxicity were calculated for 12 of the pesticides. For uncouplers, the ratios ranged from 1.7 to 8.3 with a mean ratio of 4.7. For the organophosphates, the ratios ranged from 4.5 to 27.9 with a mean ratio of 10.4.
subchronic schizophrenia definition

Sub chronic toxicity