Tapering stress dose steroids
[DOC File]Goal: Study the Effects of Glucocorticoids on the ...
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Animals in the dexamethasone group will receive intramuscular Dexamethasone in a tapering dose on PD5 and PD6 (0.5mg/kg on PD5 and 0.1mg/kg on PD6). Animals in the Hydrocortisone group will also receive tapering doses of intramuscular hydrocortisone on PD5 and PD6 (5.0 mg/kg on PD5 and 1.0mg/kg on PD6).
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These children should be treated with steroids during stress like surgery, anesthesia and serious infections. Corticosteroids can be used as parenteral hydrocortisone at a dose of 2–4 mg/kg/day or oral prednisolone at a dose of 0.3–1 mg/kg/day. This is given for the duration of stress and the same can be tapered rapidly. Summary
[DOC File]CORTICOSTEROIDS IN THE ICU:
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Steroids and biologic agents in the ICU. RP Allen, Crit Care Clinics, July 1991:695-712. Adrenal crisis. R Chin, Critical Care Clinics January 1991:23-42. The utility of parenteral glucocorticoids in the emergency department. Hoang KD , Pollack CV Jr, J Emerg Med 1994; 12:507-19. OBJECTIVE
Ohio University
As mentioned above, this is NOT a problem when the patient is taking high doses of pharmacologic steroids—it only becomes a problem when the patient “goes off” the pharmacologic steroids; for example, when a patient goes off them too quickly--without a long slow tapering off process to allow the adrenals to become “online” again (that ...
[DOC File]3
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Commonly abused steroids: Anadrol, Oxandrin, Dianobol, Winstrol, Durabolin, Depo-Testosterone, and Equipoise. There are more than 100 types of anabolic steroids, and each requires a prescription. Most common method of usage is via oral ingestion, injection or topically rubbed on the skin as a cream or gel.
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Dose: Use IV if severe (PO absorption compromised); 10-14/7 course for adults (shorter if sudden onset, rapid response), 3-5/7 for children; tapering not required unless on maintenance steroids / >2/52 course. Prednisone 25-50mg (1mg/kg) PO OD . Dexamethasone 4-8mg (0.1mg/kg) IV – IV drug of choice
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