Thyroid hormone production pathway
[DOC File]12 Cellular Communication-S - Corner Canyon AP Biology
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d. Cells in the pituitary gland produce thyroid stimulating hormone (TSH), which is received by cells in the thyroid. The arrival of TSH in the thyroid triggers production of several hor- mones, which then travel throughout the body to regulate metabolism. 10.
[DOC File]Anatomy Review: Skeletal Muscle Tissue
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The mechanism of thyroid hormone (TH) production is unique in the body. ... Families of related hormones are produced when the metabolic pathway involves the sequential modification of a basic starting molecule. The hormone produced by a given cell depends upon the enzymatic makeup of that cell.
[DOC File]Chapter 10 Principle of Hormonal Control
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Synthesis of thyroid hormones 1) Thyroid gland (Fig.11-20) Location: below the thyroid cartilage Structure Has rich blood vessels -red color Contains follicles, which produce thyroid hormone (T4, T3) Controlled by TSH from anterior pituitary gland 2) Thyroid hormone production (Fig.11-21) (1) Active transportation of iodide (I-)into follicles ...
[DOC File]Biochemistry Objectives 46
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TRH: Thyroid releasing hormone stimulates thyrotrophic release of TSH via Gq and the IP3/DAG/Ca2+ pathway. TSH: thyroid stimulating hormone T4 activation to T3 in peripheral target cells: T4 is brought into the cell by passive diffusion when bound to TBG, and is converted to the more metabolically active T3 form by 5’ deiodinase.
[DOC File]Thyroid Hormones
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Lack of thyroid hormone is likely to cause loss of libido, while great excesses can cause impotence. In women, lack of thyroid hormone often causes excessive a frequent bleedings in some women. A complex of protein, hyaluronic acid and chondroitin sulfate (mucopolysaccharide) accumulates in the extracellular space of the skin.
[DOC File]Genetic Defects in Thyroid Hormone Synthesis and Action
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Mutations in TPO gene (particularly nonsynonymous cSNPs) can lead to severe defects in thyroid hormone production, due to total or partial iodide organification defects. Based on the literature, exons 7–11 encoding the catalytic center of the TPO protein (heme binding region) are crucial for the enzymatic activity.
[DOC File]Endotext.com - Thyroid Disease Manager
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64 Medici M, van der Deure WM, Verbiest M, Vermeulen SH, Hansen PS, Kiemeney LA, et al. A large-scale association analysis of 68 thyroid hormone pathway genes with serum TSH and FT4 levels. Eur J Endocrinol. 2011 May;164(5):781-8. 65. Porcu E, Medici M, Pistis G, Volpato CB, Wilson SG, Cappola AR et al.
[DOC File]Hypothalamus and Pituitary Hormones
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Thyroid Stimulating Hormone (TSH or thyrotroph) Stimulated by TRH and indirectly by pregnancy and cold temperature. It regulates the function of the follicles of the thyroid gland. Inhibited by feedback inhibition exerted by thyroid hormones on anterior pituitary and hypothalamus and by GHIH (somatostatin) and dopamine.
[DOC File]Endocrine system
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For example, thyroid-stimulating hormone (TSH) causes growth and increased activity of another endocrine gland, the thyroid, which increases output of thyroid hormones. A recently identified class of hormones is that of the "hunger hormones" - ghrelin, orexin, and PYY 3-36 - and "satiety hormones" - e.g., cholecystokinin, leptin, nesfatin-1 ...
Oklahoma State University–Stillwater
in the thyroid gland, is the process of incorporation or binding of oxidized iodine into the thyroglobulin tyrosine residues for the production of thyroid hormone. During this step, the inactive thyroid hormone forms are synthesized, monoiodotyrosine (MIT) and diiodotyrosine (DIT).
[DOC File]ENDOCRINE SYSTEM - Weebly
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ENDOCRINE SYSTEM. Hormone. Produced by. Target Action. HGH [growth hormone, somatotropin] anterior pituitary stimulates bone & muscle growth, protein anabolism, fat catabolism, glycogenolysis, liver synthesis of somatomedins TSH [thyroid stimulating hormone, thyrotropin] anterior pituitary stimulates synthesis & secretion by the thyroid ACTH [adrenocorticotropic hormone, adrenocorticotropin ...
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