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[DOC File]Pulmonary - Stanford University
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Thrombolysis drugs FDA-approved dose Alternative dose Cost Streptokinase 250,000 U bolus over 20 min 100,000 U/hr over 24-72 hr 1,500,000 U over 1 hr $350 Urokinase 4,400 U/kg bolus, 4,400 U/kg/hr for 12 hr 3,000,000 U over 2 hr $2000-$2700 TPA 100 mg over 2 hours 0.6 mg/kg over 3-15 min $2000-$4200 Wells Messersmith, M.D. Andrew Yee, M.D.
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[DOC File]Pediatric Stroke Program - Pediatric Residency Program: JAX
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Intravenous TPA dose is 0.9 mg/kg (maximum dose is 90 mg) 10 % given over 1 minute bolus , with reminder 90% given over 1 hour-a separate dedicated line is required for tPA-hold all anti-coagulation and anti-platelet agents for at least 24 hours. Major adverse effect of tPA is intracranial hemorrhage:
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[DOC File]Drug
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CI—liver dz Requires monitoring PT time (INR) Alteplase Recombinant tPA (activates plasmin on fibrin) DOC for acute MI. DVT & PE IV dosing w/in 4-6h Anistreplase Streptokinase-plasminogen complex (NOT specific to fibrin) Acute MI Derived from Strep
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[DOC File]I-SPOT Exclusion Medication List - NETT
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IV tPA is allowed in I-SPOT Protocol Version 2 ... Low Molecular Weight Heparins (LMWH) at therapeutic or full dose for DVT/PE or other indications. Bemiparin (Hibor/Ivor/Badyket) Certoparin (Embolex/Sandoparin) ... DVT prophylaxis with subcutaneous LMWH allowed. Fondaparinux (Arixtra) at therapeutic or full dose. Note: DVT prophylaxis with ...
massive pe tpa

[DOC File]PEDIATRIC CARE GUIDE
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Continuous infusion: titrate dose to 0.04-0.16 mg/kg/hour for 2-5 days in children. Flumazenil: Conscious sedation reversal: initial dose: 0.01 mg/kg (max dose: 0.2 mg) give over 15 sec; may repeat 0.01 mg/kg (max dose: 0.2 mg) after 45 sec, then every min to max total dose of …
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[DOC File]CARDILOGY MCQ
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tPA has significantly better outcomes at two hours. 41.Some education: the PIOPED study . Prospective Investigation of Pulmonary Embolism Diagnosis. compared VQ scan to angiogram. results released in 1990. VQ scan (low intermediate or high probability) = 98% sensitive for PE but only 10% specific - ie many pts without PE also had these results
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[DOCX File]EM Basic | Your Boot Camp Guide to Emergency Medicine
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Thrombolytics for sub-massive PE bottom line:- Half dose thrombolytics in those with sub-massive PE who are young and healthy with good functional status and no risk factors for increased bleeding (usual TPA contraindications) is probably a good idea and something you should offer to the patient
tpa for pe guidelines

[DOC File]ITE Review: Cardiovascular
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-TPA preferred, 100mg over 2 hours. Pericardial Disorders. Pericarditis-most common cause: idiopathic and viral-diagnosis-Hx: sharp precordial pain, relieved by sitting up and leaning forward-PE: friction rub is pathognomonic (triphasic, lower left sternal border)-EKG: diffuse concave up ST elevation with PR depression-echo: to look for effusion
tpa treatment for pulmonary embolism

[DOC File]EVIDENCE-BASED PRACTICE PROTOCOL
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EVIDENCE-BASED PRACTICE PROTOCOL. Prevention and Management of Deep Vein Thrombosis (DVT) Definitions A DVT is the formation of a blood clot that …
low dose tpa for pe

[DOCX File]WordPress.com
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tPA vs placebo for NIHSS scores / mortality / probability of favourable outcome in CVA. ... Low dose dopamine for renal protection (Lancet, 2000) ... CCF, trauma, PE, Ca (more likely if large), autoimmune, renal failure. R = ovarian Ca. L = pancreatitis, chylothorax, CCF.
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Tpa dose for pe