Treatment for statin muscle pain

    • [DOC File]Q&A xx - UKMi

      https://info.5y1.org/treatment-for-statin-muscle-pain_1_577547.html

      As with all statins, patients should be instructed to report any unusual or unexplained muscle tenderness, pain or weakness to their healthcare provider immediately. In patients with moderate-severe renal impairment (e.g. GFR less than 59 mL/min/1.73 m2) or those taking concomitant rifampin, the initial daily dose of pitavastatin should be 1 mg ...

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    • [DOC File]STATIN-FIBRATE REPORT: Focus on Safety

      https://info.5y1.org/treatment-for-statin-muscle-pain_1_b26651.html

      NICE noted that the studies have focussed on the reduction of muscle pain and while muscle pain may be a problem for some people, adherence is a common problem with all medications (20). Summary. There is some limited evidence which suggests that CoQ10 supplementation with statin treatment may improve statin-associated muscle symptoms.

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    • [DOC File]UKMi Q&A xx - SPS

      https://info.5y1.org/treatment-for-statin-muscle-pain_1_528142.html

      The second is that statins can occasionally affect the muscles, causing muscle pain or weakness, and leakage of the muscle enzyme creatine kinase into the blood stream. This muscle problem is reversible if the tablets are stopped, but can rarely lead to widespread muscle breakdown (known as rhabdomyolysis) with kidney problems, and very rarely ...

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    • [DOC File]Cholesterol - Hormone Restoration

      https://info.5y1.org/treatment-for-statin-muscle-pain_1_ac3a88.html

      Whilst on treatment If muscle pain, weakness or cramps occur whilst a patient is receiving treatment with a statin, their CK levels should be measured. If these levels are found, in the absence of strenuous exercise, to be significantly elevated (> 5 x ULN), treatment should be stopped.

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    • [DOC File]FACTS ABOUT STATINS

      https://info.5y1.org/treatment-for-statin-muscle-pain_1_61ff86.html

      The condition tends to respond favourably to treatment, with improvement in muscle strength and reduction of CK. Due to the rarity of statin-induced autoimmune myositis, specialist experience usually guides the choice of immunosuppression, although methotrexate, azathioprine and mycophenolate are probably the most commonly used.

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    • [DOC File]Pharmacy Benefits Management Services Home

      https://info.5y1.org/treatment-for-statin-muscle-pain_1_eeaab2.html

      The aim of this study is to determine whether coenzyme Q10 supplementation would reduce the degree of muscle pain associated with statin treatment. Patients with myopathic symptoms were randomly assigned in a double-blinded protocol to treatment with coenzyme Q10 (100 mg/day, n = 18) or vitamin E (400 IU/day, n = 14) for 30 days.

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    • NATIONAL INSTITUTE FOR CLINICAL EXCELLENCE

      Any patient taking a statin (other than pravastatin) who is given miconazole oral gel should be warned to watch for signs of myopathy (i.e. unexplained muscle pain, tenderness or weakness or dark coloured urine). If myopathy does occur the statin should be stopped immediately. Background

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    • [DOC File]SPS

      https://info.5y1.org/treatment-for-statin-muscle-pain_1_3c63f0.html

      The number of subjects reporting muscle pain at the end of treatment was higher with CoQ10 treatment: 70% vs. 38.8%, p=0.05. Time to pain onset was similar between the groups (3.0±2.0 weeks vs. 2.4±2.1 weeks; p=0.55). In the cross-over Phase 2 study (n=24), there were no differences in PSS and PIS, or pain at the end of statin treatment.

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    • [DOCX File]Title: Statin Induced Autoimmune Myopathy

      https://info.5y1.org/treatment-for-statin-muscle-pain_1_0a478f.html

      However, in the largest study (n = 20,536), similar numbers of participants in the statin and placebo treatment groups experienced unexplained muscle pain or weakness. Continuation and compliance Rates of continuation with statin therapy were approximately 87%, after 3 years of treatment in the primary prevention trials, and approximately 75% ...

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    • Managing statin muscle pain - Harvard Health

      Myositiis: Muscle symptoms (pain, tenderness and/or weakness) with CK elevation. Myopathy: General term referring to any disease of the muscle (acquired or inherited). Rhabdomyolysis: Muscle symptoms with significant CK elevation (typically more than 10 times the upper limit of normal).

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