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[DOC File]Jaundice or elevated bilirubin - Pennine VTS
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j - Contrast conjugated and unconjugated bilirubin. k- Discuss the possible causes for altered bilirubin metabolism. 1- Predict the consequences of hepatic disease including obstruction, cellular damage and portal hypertension.
causes of unconjugated hyperbilirubinemia

Conjugated & unconjugated bilirubin, causes & treatment of direc…
Unconjugated bilirubin bound to albumin is transported to the liver, where it is taken up by hepatocytes via a process that partly involves carrier-mediated membrane transport. In the liver, bilirubin is conjugated to glucuronic acid by bilirubin glucuronosyltransferase. This bilirubin is conjugated, direct, and soluble in water.
unconjugated bilirubin high

[DOCX File]DEPARTMENT OF PHYSIOLOGY - KSU
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Conjugated bilirubin causes kernicterus in adults. b. Unconjugated bilirubin does not colour sclera. c. Unconjugated bilirubin is tightly bound to albumin
conjugated vs unconjugated hyperbilirubinemia

Key Points_Gastro 8 - Ohio University
Check: LFTs, conjugated v unconjugated bilirubin, haemoglobin, reticulocyte count. Criteria. Bilirubin fluctuates but
unconjugated jaundice

[DOC File]University of Toronto
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c. free (unconjugated) bilirubin is transported by albumin. d. bilirubin is transported to the liver and conjugated with: 1. glucuronic acid to form bilirubin glucuronide (80%) 2. sulfate to form bilirubin sulfate (10%) e. bilirubin is excreted from the hepatocytes by an active transport process into the bile canaliculi and into the intestines. f.
what is unconjugated bilirubin

The Liver As An Organ - Parker University
Conjugated bilirubin causes kernicterus in adults. Unconjugated bilirubin does not colour sclera. Unconjugated bilirubin is tightly bound to albumin. Unconjugated bilirubin produces bilirubin in urine. Conjugated bilirubin is tightly bound to albumin. In cirrhosis. fibrosis is confined to the delicate bands around central veins. nodularity is ...
unconjugated bilirubinemia

[DOC File]Jaundice or elevated bilirubin
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In hemolytic anemias, the hepatocytes are capable of “taking in” and conjugating bilirubin, but they are “overwhelmed” by the great excess of unconjugated bilirubin “free-ed up” by the excessive breakdown of red cells; thus, jaundice can occur, made up mostly of unconjugated bilirubin;
where is unconjugated bilirubin formed

[DOC File]GI—Introduction to GI and Bilirubin
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Bilirubin will be higher if patient fasting or during intercurrent illness. Ask for conjugated v. unconjugated bilirubin: the hyperbilirubinaemia should be largely unconjugated, but don’t trust the laboratory ranges for conjugated bilirubin, they are too strict, and many Gilberts patients have an elevated conjugated bilirubin.
unconjugated hyperbilirubinemia adult

[DOCX File]WordPress.com
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Bilirubin. produced in the spleen via the lysis of old RBCs. unconjugated (hydrophobic) so it binds to albumin in the blood stream. conjugated in the liver by adding two molecules of glucuronic acid. secreted in bile into small intestine. converted by gut flora to bilinogen. reabsorbed into bloodstream or excreted in feces (stercobilinogen)
causes of unconjugated hyperbilirubinemia

Unconjugated bilirubin causes