Uterine cancers cae study

    • Do women with endometrial cancer have uterine serous carcinoma?

      Gehrig et al analyzed 1166 women with endometrial cancer, of whom 54 (5%) also had a prior history of breast cancer.7 The authors noted a 2.6- fold increase in the diag- nosis of uterine serous carcinoma among women with a history of breast cancer in this single institution study.

    • What are the risk factors for uterine serous carcinoma?

      Specific risk factors for uterine serous carcinoma include a personal history of breast cancer, tamoxifen exposure, and hereditary cancer syndromes. Common clinical features include older age and higher stage at diagnosis, and mutations in p53.

    • How is endometrial cancer diagnosed?

      The standard diagnostic evaluation for endometrial cancer includespelvic ultrasonography, office endometrial biopsy, or dilatation and cu-rettage (D&C) with or without hysteroscopy. Pelvic ultrasound is notnecessary if a patient has undergone a previous endometrial samplingshowing an invasive cancer.

    • [PDF File]Uterine Cancer Trials in Progress - Gynecologic Oncology Group

      https://info.5y1.org/uterine-cancers-cae-study_1_c308b9.html

      uterine cancer entity. The Cancer Genome Atlas performed compre-hensive molecular profiling of 373 endometrial cancers, including serous carcinomas. The serous and serous-like tumors clustered to the ‘copy number high’ sub-group. Compared with endo-metrial tumors of the other molecular sub-groups, these tumors are defined by genomic ...

    • [PDF File]Uterine serous carcinoma: key advances and novel treatment ...

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      INTRODUCTION Uterine serous carcinoma is an uncommon cancer that continues to have a significant effect on patient outcomes and survival. High rates of extra- uterine disease at diagnosis, combined with a paucity of effective therapies, have limited our ability to make meaningful progress in the treatment of women with uterine serous carcinoma.

    • [PDF File]Endometrial cancer: A review and current management ...

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      • We present risk factors for endometrial cancer, including genetic predisposition. • We review the diagnostic and metastatic evaluation of women with endometrial cancer. • We describe the surgical management of early and advanced endometrial cancer.

    • [PDF File]Getting serious about serous endometrial cancer: should we ...

      https://info.5y1.org/uterine-cancers-cae-study_1_62c166.html

      stage uterine serous carcinoma is not defined. The goal of this study was to investigate the impact of adjuvant treatment on survival of patients with tumors confined to the endometrium. Methods Patients diagnosed with stage I uterine serous carcinoma with no myometrial invasion between January 2004 and December 2015 who underwent hysterectomy

    • [PDF File]Review Adjuvant therapy for endometrial cancer

      https://info.5y1.org/uterine-cancers-cae-study_1_030dbb.html

      ABSTRACT. Endometrial cancer is primarily treated with surgery. Adjuvant treatment strategies for endometrial cancer, such as external beam pelvic radiotherapy, vaginal brachytherapy, chemotherapy, and combined chemotherapy and radiotherapy, have been studied in several randomized trials.

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