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[DOC File]Draft Guidelines for Surgical Procedure Antibiotic Prophylaxis
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Antibiotic Class MOA Antibacterial Spectrum Penetration Clearance Adverse Effects / Contraindications Special Considerations INHIBITORS OF CELL WALL SYNTHESIS ... Vancomycin. Inhibits CWS at an earlier step than the β-lactams. Gram+; ... Slow IV drip, orally only for . C. difficile colitis. INHIBITORS OF PROTEIN SYNTHESIS Gentamicin.
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[DOC File]Apparent source of sepsis
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Although Vancomycin has been recommended in the Trust’s general antibiotic treatment policy, its administration involves a prolonged administration time of 100- 120 minutes. Given the importance of proper timing of antibiotic administration in Surgical Prophylaxis, and also for logistical and possibly nephroptoxicity reasons, Teicoplanin ...
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[DOC File]Prophylaxis of Surgical Site Infections
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In this case, while vancomycin and ceftriaxone both have activity against the organism, penicillin is the preferred choice given its narrow spectrum, excellent activity against the organism, and low side-effect profile. It would both be appropriate and safer for your patient for vancomycin and ceftriaxone to be de-escalated to penicillin.
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[DOCX File]Antibiotics for Open Fractures - UW TASP
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A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin. Microbiology 2010; 156: 3354-9. Louie TJ et al. OPT-80 eliminates Clostridium difficile and is sparing of Bacteroides species during treatment of C.difficile infection.
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[DOCX File]AHRQ Safety Program for Improving Antibiotic Use
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Persistently positive blood cultures while on IV vancomycin therapy (of note, mean duration is 7 days for vancomycin-treated MRSA bacteremia in endovascular [i.e., endocarditis] infection) OR Inability to tolerate vancomycin therapy due to allergy (excluding red man’s syndrome) or a current episode of moderate to severe acute kidney injury (AKI)
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[DOCX File]Northwestern Medicine Antimicrobial Stewardship
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Vancomycin 1.5g iv 12-hourly. plus. Ceftriaxone 1g iv 24-hourly Vancomycin 1-1.5g iv 12-hourly. plus. Ciprofloxacin 400mg iv 12-hourly above. ... Metronidazole 500mg iv 12-hourly. Northern Health Antibiotic Guide for Severe Infection. These guidelines are for severe infections. Please see the NH Antibiotic Guidance program and Australian ...
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[DOC File]Vancomycin Revisited: A Reappraisal of Clinical Use
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Correct antibiotic prophylaxis depends on the severity of the injury and epidemiological risk factors. Combined with expert surgical technique, early administration of antibiotics is likely the most important factor in preventing infection. ... For patients < 70kg: vancomycin 1 gram IV q 12 hours x 2 doses (24 hours), first dose now.
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Side Effects of Vancomycin IV | Healthfully
Vancomycin is eliminated by glomerular filtration. The serum half-life of IV vancomycin is 6 hours with normal renal function, and 7 days in anuria [1], [6], [56], [62]. Many approaches to vancomycin dosing for various degrees of renal insufficiency have been devised and all are based on CrCl [1], [6], [21].
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[DOC File]Fidaxomicin Monograph - Veterans Affairs
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Antibiotic prophylaxis with vancomycin and ciprofloxacin should be initiated 60-120 minutes before the first incision is made, since vancomycin is infused at a rate of 1 gram per hour. When a proximal tourniquet is used, recommended guidelines state the entire infusion should be completed prior to inflation of the tourniquet.
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Vancomycin antibiotic iv