Vancomycin dosing and monitoring guidelines
[PDF File]Vancomycin Monitoring and Dosing Guideline
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Vancomycin Monitoring and Dosing Guideline Contact your local laboratory for hours of service or visit MyHealth.Alberta.ca Version: 1.2 Effective Date: 26 November 2018 RCCGNR15154 Edmonton Zone Chemistry Page 2 of 2 Infection Desired Trough Level (mg/L) Osteomyelitis 15-20 Pneumonia CNS infections ...
[PDF File]Vancomycin Pharmacokinetics, Dosing & Therapeutic Drug ...
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2009 Vancomycin Guidelines. 11. Rybak et al. Am J Health Syst Pharm. 2009. Vancomycin is a . concentration-independent . killer of gram-positive pathogens • AUC/MIC is the most useful PK/PD parameter to predict efficacy. Trough serum vancomycin concentrations considered most practical method for monitoring • Drawn at steady state, just ...
Vancomycin Dosing and Monitoring Guidelines - Adult Patients
Vancomycin Dosing and Monitoring Guidelines - Adult Patients 1) Determine empiric dose Loading dose: 20mg/kg (rounded to nearest 250mg, maximum 2 grams) Recommended for difficult-to-treat infections (endocarditis, osteomyelitis, meningitis, hospital acquired pneumonia caused by S. aureus), or in any scenario in which rapid achievement of
Therapeutic monitoring of vancomycin for serious ...
on vancomycin as it related to in vitro and in vivo pharmacokinetic and phar-macodynamic (PK/PD) characteristics, including information on clinical effi-cacy, toxicity, and vancomycin resistance in relation to serum drug concentration and monitoring. The data were summar-ized, and specific dosing and monitoring recommendations were made. The pri-
[PDF File]Vancomycin Therapeutic Drug Monitoring
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Vancomycin Regimens Vancomycin can be given as: 1. Intermittent dosing (standard) – (see page 4-5) 2. Continuous infusion (ITU patients only) – (see page 5 Do not dose at midday or midnight Aim for (10am and 10pm) or (6am and 6pm) for 12 hourly dosing (10am or 2pm) for 24 hourly/ 48 hourly dosing General rules for Vancomycin Monitoring
[PDF File]UWHC Guidelines for the Use of Vancomycin - May 2018 - PT ...
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2. The dosing of vancomycin for included patient populations should be based upon recommendations outlined in Table 1. In general, weight-based loading doses are utilized followed by maintenance dosing based on weight, renal function, and indication. 3. Monitoring of vancomycin therapy should include:
Vancomycin Dosing Guidelines - University Health
Vancomycin Dosing for Adults University Health System Necessary Patient Information for Dosing Actual body weight –the use of actual body weight is recommend for vancomycin dosing CrCl – vancomycin is almost exclusively renally cleared and must be renally adjusted o CrCl = (140-age) x (wt in kg) x 0.85 if female 72 x SCr
[PDF File]Vancomycin prescribing and monitoring guidelines for PICU
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Vancomycin prescribing and monitoring guidelines for PICU Author: colec2 Created Date: 7/18/2017 5:07:41 PM ...
[PDF File]VANCOMYCIN NOMOGRAM FOR ADULT PATIENTS: GOAL AUC24 400-600
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significant impact on vancomycin distribution or clearance (e.g., pregnancy, severe trauma, ascites, extensive fluid boluses, etc.). Please reduce total daily vancomycin dose by approximately 30% when treating patients with uncompensated cirrhosis. Monitoring within 72 hours of starting vancomycin: 1.
[PDF File]SBUH Guidelines for Vancomycin Serum Concentration Monitoring
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• Monitor by pre-hemodialysis level (see SBUH Vancomycin Dosing Guidelines for monitoring targets) • If the same post-hemodialysis dose is given for 2 consecutive hemodialysis sessionsin achieving the pre-HD target, that same dose can be given after each hemodialysis thereafter. Monitoring can be extended to once a week or once every 2 weeks.
[PDF File]Vancomycin Dosing and Monitoring Guidelines - Adult Patients
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Vancomycin Dosing and Monitoring Guidelines - Adult Patients Standard vancomycin dosing (target trough 10-15mcg/mL) 1) Determine Dose Total Body Weight Dose Infusion time 50-80 kg 1000mg Infuse over 60 minutes >80 – 100 kg 1250mg Infuse over 90 minutes 100-120 kg 1500mg Infuse over 2 hours 2) Determine Dosing Interval Creatinine Clearance
Vancomycin Dosing and Monitoring in Adults Clinical Guideline
Vancomycin Dosing and Monitoring in Adults. 1. Introduction . Vancomycin is a glycopeptide antibiotic. Intravenous formulations are used to treat infections with Gram-positive bacteria and for surgical prophylaxis in some situations. The SA Medicines Formulary restricts use of intravenous vancomycin to the following indications in adults: >
IV Vancomycin dosing and monitoring Antibiotic Guidelines
IV Vancomycin dosing and monitoring Antibiotic Guidelines Reference Number: 144TD(C)25(H3) Version Number: 6.1 Issue Date: 21/07/2020 Page 3 of 12 It is your responsibility to check on the intranet that this printed copy is the latest version This document refers to the treatment of adult patients (unless otherwise stated).
[PDF File]VANCOMYCIN DOSING AND MONITORING GUIDELINES
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VANCOMYCIN DOSING AND MONITORING GUIDELINES (NB Provincial Health Authorities Anti-Infective Stewardship Committee ) GENERAL COMMENTS • Vancomycin is a glycopeptide antibiotic with bactericidal activity • It is active against gram -positive bacteria, including methicillin-resistant staphylococcus (MRSA)
[PDF File]INTRAVENOUS VANCOMYCIN DOSING/MONITORING IN ADULTS OBJECTIVE
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AUC-BASED VANCOMYCIN MONITORING Guideline recommendations for AUC-based vancomycin dosing are for severe MRSA infections. The specific AUC targets for all vancomycin dosing will be used with the assumption that if a target that is validated for use in severe infections is achieved, it will also be adequate for less severe infections.
[PDF File]Vancomycin Dosing and Monitoring for Pediatric Patients
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Vancomycin Dosing and Monitoring for Pediatric Patients Guidelines developed by UWHC Department of Pharmacy Author: Jill Strayer, PharmD, James Conway, MD Reviewed by: Antimicrobial Subcommitee Approved by P&T Committee: August 2009 Next Scheduled Review Date: August 2011 A. Background/Indications
[PDF File]INTRAVENOUS VANCOMYCIN DOSING AND MONITORING GUIDELINES
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ADULT INTRAVENOUS VANCOMYCIN DOSING AND MONITORING GUIDELINES DOSE: Adult dose: (based on actual body weight (ABW))*,^: 12.5 to 15 mg/kg (round off to nearest 250 mg increment, to max dose of 1500mg; see dosing table) * If ABW is > 30% ideal body weight (IBW), then use adjusted body weight = IBW + 0.4(Total body weight - IBW) IBW Males = 50 kg + 2.3 kg for each inch > 60 inches IBW Females ...
Therapeutic Monitoring of Vancomycin in Adult Patients
Optimal monitoring parameter Trough serum vancomycin concentrations are the most accurate and practical method for monitoring efficacy. IIB Therapeutic vancomycin drug monitoring, Peak versus trough concentrations Timing of monitoring Troughs should be obtained just prior to the next dose at steady-state conditions (just before the fourth dose).
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