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[DOCX File]Introduction
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2. Trough levels should be drawn on all obese patients. Vancomycin is cleared much faster in this population vs the non-obese population. Hence, the need for q8hr dosing is not unusual when renal function is normal.
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Vancomycin. Loading Dose: 15 mg/kg over 1 hour Infusion Rate 30 mg/kg over 24 hours (adjusted to obtain trough concentrations of 20-25 mcg/mL) Special considerations. Adjust total daily dose in 500 mg increments. Measure trough concentration every 24 hours until two consecutive levels are obtained within the desired range. REFERENCES
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SHC Vancomycin Dosing Guide
Extensive use over time has demonstrated vancomycin is not nephrotoxic even when used in high dosage, i.e., twice the usual dose. Since vancomycin is not nephrotoxic, there is no rationale for dosing vancomycin based on serum vancomycin levels. Since vancomycin is eliminated by GFR, vancomycin dosing should be based on creatinine clearance.
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Deaconess - Hospitals in Evansville, IN - Deaconess Hospital
NY -- I would try to keep trough levels around 20. I do not use high peak levels to adjust dosing. LA -- Most of vancomycin "failures" (especially in ESRD or OPAT patients) is due to inappropriate serum levels. NM -- There should be an option for both increasing the dose of vanco and adding other agents
vancomycin dose adjustment trough

[DOCX File]www.testmenu.com
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BUN/SCr every other day if Zosyn and Vancomycin combination given. BUN/SCr Daily for anyone on concomitant nephrotoxic drugs, q8h dosing, or doses > 1500mg, and 48-72h after contrast, or if Zosyn and Vancomycin and concomitant condition (sepsis, SBP20, received contrast) Aminoglycosides
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[DOC File]Vancomycin Revisited: A Reappraisal of Clinical Use
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Individualizing vancomycin dosing regimens: an evaluation of two pharmacokinetic dosing programs in critically ill patients. ... Acute renal injury and vancomycin levels in patients undergoing autologous hematopoietic stem cell transplantation. Biology of Blood and Marrow Transplantation.
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[DOC File]ICU SEDATION GUIDELINES
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Random vancomycin levels are useful only for patients with renal insufficiency and when two separate random levels are measured in a dosing cycle; with two distinct levels, the time when the level will be 5 to 15 g/mL can be estimated, and the next dose can be given at that time.
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[DOC File]CIRB Review Application
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Look for and target normal ionized calcium levels (1.2 – 1.4mmol/L), specifically in patients of arrhythmia / shock / trauma / actively bleeding / massive transfusions. Correct with IV Calcium through CVL: check for dose as per nurses guide / iClip.
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[DOC File]“ALL MICROBIOLOGY IS LOCAL
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, an actinomycete isolated from soil samples in Indonesia and India. Vancomycin is a glycopeptide with bactericidal action that acts by inhibiting peptidoglycan synthesis in the c
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[DOCX File]ANZCTR
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Daily vancomycin reports will be run by investigators to identify potential study subjects who meet inclusion/exclusion criteria for our cohort. Those patients identified will be approached regarding consent to the drawing of two additional vancomycin levels beyond the …
dosing vancomycin based on trough levels

Vancomycin dosing two levels