Vancomycin dosing update
What is the maximum dose of vancomycin?
In non-obese adults with normal kidney function, they recommend a loading dose of 20-35mg/kg/day, with a maximum dose of 3000mg given in a single dose. For non-obese children and neonates, a loading dose is not recommended. If the adult patient is obese, loading doses of 20-25mg/kg using actual body weight, up to 3000mg may be considered.
What is the renal dose of vancomycin?
The dosage of vancomycin per day in mg is about 15 times the glomerular filtration rate in mL/min: The initial dose should be no less than 15 mg/kg, even in patients with mild to moderate renal insufficiency. The table is not valid for functionally anephric patients.
How to adjust vancomycin dose?
•If the high trough level appears genuine, use the vancomycin dose adjustment calculator to obtain a new dosage regime. Consider omitting dose based on the level: - If vancomycin trough level is 20-25mg/L, give new dosage regime without omitting any doses. Take a level before the 4th new dose.
What are the long term effects of vancomycin?
sores, ulcers, or white spots in the mouth or on the lips sweating swollen glands unusual bleeding or bruising Side effects not requiring immediate medical attention Some side effects of vancomycin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine.
[PDF File]Intravenous Vancomycin Use – Adult – Inpatient/Ambulatory ...
https://info.5y1.org/vancomycin-dosing-update_1_e8d147.html
ADULT INTRAVENOUS VANCOMYCIN DOSING AND MONITORING GUIDELINES DOSE: Adult dose: (based on actual body weight (ABW))*,^: 12.5 to 15 mg/kg (round off to nearest 250 mg increment, to max dose of 1500mg; see dosing table) * If ABW is > 30% ideal body weight (IBW), then use adjusted body weight = IBW + 0.4(Total body weight - IBW)
[PDF File]SHC Vancomycin Dosing Guide - Stanford Medicine
https://info.5y1.org/vancomycin-dosing-update_1_a96518.html
Feb 22, 2023 ·
[PDF File]Vancomycin Dosing for Adults - University Health System
https://info.5y1.org/vancomycin-dosing-update_1_fc79e8.html
Parenteral administration of vancomycin is not effective for treatment of staphylococcal enterocolitis and C. difficile-associated diarrhea. If parenteral vancomycin therapy is desired, use an intravenous preparation of vancomycin and consult the package insert accompanying that preparation. 5.2 Potential for Systemic Absorption
ASHP
The objective of this guideline is to improve the use of vancomycin by optimizing the evaluation of the clinical necessity for vancomycin therapy, dosing of vancomycin dosing based on pharmacodynamic and pharmacokinetic principles and parameters, and the monitoring of vancomycin, including therapeutic drug monitoring. Target Population:
[PDF File]HIGHLIGHTS OF PRESCRIBING INFORMATION ...
https://info.5y1.org/vancomycin-dosing-update_1_4243e0.html
SHC Vancomycin Dosing Guide A: Initial dosing considerations B. Pharmacodynamic Targets: goal AUC and troughs C. Loading dose D: Initial Vancomycin Maintenance Dosing and Serum Concentration Monitoring E: Dose Revisions F: Intermittent Hemodialysis Dosing Algorithms G: Continuous Infusion Vancomycin H: PK equations I: Discharge on vancomycin
[PDF File]INTRAVENOUS VANCOMYCIN DOSING AND MONITORING GUIDELINES
https://info.5y1.org/vancomycin-dosing-update_1_40dbc5.html
1.5 x 1 dose 1.75 x 1 dose 2 x 1 dose 2.5 x 1 dose Maintenance Doses Follow below algorithm for initial vancomycin doses based on weight and renal function GOAL TROUGH: 10-20 mcg/mL Creatinine Clearance (mL/min) ABW** (kg) Scheduled HD (3 x times weekly)
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