Viral causes of cardiomyopathy
[PDF File]acute viral myocarditis: current concepts in diagnosis and ...
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tion – from acute disease to dilated cardiomyopathy [3-8,10]. Both innate and adaptive immune responses are crucial deter - minants of the severity of myocardial damage. A genetic pre-disposition has also been hypothesized. etiologY oF acute viral mYocarditis – tHe viral sHiF t In the mid- and late 1990s, enteroviruses, particularly coxsackie
[PDF File]Myocarditis: the causes
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Chronic myocarditis and inflammatory cardiomyopathy Acquired viral cardiomyopathy A virus-associated cardiomyopathy develops if, due to an inadequate immune response, the acquired virus is not cleared successfully or if transcriptional virus activity persists. Viral persistence can expose the host to persistent antigenic trigger and chronic
[PDF File]What Is Cardiomyopathy?
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What Is Cardiomyopathy? Cardiomyopathy (KAR-de-o-mi-OP-ah-thee) refers to diseases of the heart muscle. These diseases have many causes, signs and symptoms, and treatments. In cardiomyopathy, the heart muscle becomes enlarged, thick, or rigid. In rare cases, the muscle tissue in the heart is replaced with scar tissue.
[PDF File]Autosomal Recessive Cardiomyopathy Presenting as Acute ...
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acute viral myocarditis (AVM). Of note, clinical severity is uncorrelated with viral infectious causes, suggesting a human genetic predisposition. Studies in inbred mice have implicated the major histocompat-ibility complex and other loci in genetic susceptibility to Coxsackie virus-induced myocarditis(3,4). Overall,
[PDF File]Patient Information Non-Ischemic Cardiomyopathy
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• Non-Ischemic cardiomyopathy is a generic term which includes all causes of decreased heart function other than those caused by heart attacks or blockages in the arteries of the heart. • The most common causes of non-ischemic cardiomyopathy are viral infection (viral myocarditis), drug
[PDF File]Roles of Host Immunity in Viral Myocarditis and Dilated ...
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The pathogenesis of viral myocarditis includes both the direct damage mediated by viral infection and the indirect lesion resulted from host immune responses. Myocarditis can progress into dilated cardiomyopathy that is also associated with immunopathogenesis. T cell-mediated autoimmunity, antibody-mediated autoimmunity (autoantibodies), and ...
DILATED CARDIOMYOPATHY - American Heart Association
Dilated cardiomyopathy can appear along a spectrum of no symptoms, subtle symptoms or, in the more severe cases, congestive heart failure (CHF), which occurs when the heart is unable to pump blood well enough to meet the body tissue needs for oxygen and nutrients. When only subtle symptoms exist, infants and young children are sometimes diagnosed with a viral upper respiratory tract infection ...
[PDF File]Diagnosis and management of dilated x cardiomyopathy
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dilated cardiomyopathy (IDC). There are experimental and clinical data in animals and humans suggesting that genetic, viral, and immune factors contribute to the pathophysi-ology of IDC. Diagnosis Clinical presentation The first presentation of IDC may be with systemic embolism or sudden death, but patients more typically present with signs and
[PDF File]Incidence, Causes, and Outcomes of Dilated Cardiomyopathy ...
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Incidence, Causes, and Outcomes of Dilated Cardiomyopathy in Children Jeffrey A. Towbin, MD April M. Lowe, MS Steven D. Colan, MD Lynn A. Sleeper, ScD E. John Orav, PhD Sarah Clunie, RN Jane Messere, RN Gerald F. Cox, MD, PhD Paul R. Lurie, MD Daphne Hsu, MD Charles Canter, MD James D. Wilkinson, MD Steven E. Lipshultz, MD C ARDIOMYOPATHIES ARE ...
[PDF File]Factors Associated With Establishing a Causal Diagnosis ...
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screened systematically for causes of cardiomyopathy in selected groups of children have identified a variety of metabolic, mitochondrial, and viral causes in substantial proportions of patients.8 Importantly, the condition of children with cardiomyopathy has improved …
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