What does acute toxicity mean
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The Approved Criteria combines acute with chronic toxicity for some hazard categories (i.e. N51 does not exist as an individual classification). However, the GHS Classification Criteria separates acute and chronic hazard classes.
[DOCX File]Guidance on the Classification of Hazardous Chemicals ...
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Acute toxicity is the ability of a chemical to cause ill effects relatively soon after one oral administration or a 4-hour exposure to a chemical in air. "Relatively soon" is usually defined as a period of minutes, hours (up to 24) or days (up to about 2 weeks) but rarely longer.
[DOC File]Dirty Business - American Chemical Society
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The acute toxicity test was performed for 4 days in which two replicates of seven different Zn concentrations (0, 10, 40, 70, 100, 130, and 160 mg/L) were used (10 fish for each aquarium). At 24, 48, 72, and 96 h, fish dead were counted in the different Zn concentrations along with the control group.
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Acute Toxicity Any poisonous effect produced by a single short-term exposure. The LD50 of a substance (the lethal dose at which 50 percent of test animals succumb to the toxicity of the chemicals) is typically used as a measure of its acute toxicity.
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CHAPTER 11 34. Despite their acute toxicity, the new synthetic insecticides are made widely available to consumers. What kinds of products are sold to the public? How are they advertised? 35. What kinds of warnings about their toxicity (acute or long-term) are provided on their labels? 36.
[DOC File]Acute toxicity of zinc in Nile tilapia fingerlings
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Acute Pulmonary Toxicity and Pathogenicity - [species] [OR if not review of study report, then insert “Waiver Request”, “Review of Published Study” or “Review of Published Literature”] NAME OF TGAI, MP or EP / NAME OF A.I. (Chemical code)/
[DOC File]GLOSSARY - FEMA
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B. REVIEWER’S COMMENTS: The reviewer agrees [does not agree] with the study author’s conclusion. [Formulation] meets the requirements for EPA Toxicity Category [I, II, III or IV] for acute oral toxicity.
[DOC File]United States Environmental Protection Agency | US EPA
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Acute Oral Toxicity– [species] [OR if not review of study report, then insert “Waiver Request”, “Review of Published Study” or “Review of Published Literature”] NAME OF …
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Acute toxicity is the result of a one-time, short-term, significant-dose exposure to a substance. So, for example, we sometimes hear about railroad tank cars containing a poisonous substance (like chlorine) overturning as the result of a derailment or other accident.
Definition of Toxicity
Toxicity based on the LD50 in males or females which ever is lower, or lack of deaths at the limit dose) EPA Toxicity Category I, II, III, IV. Label comment if applicable. This acute oral study is classified as acceptable. It does satisfy the guideline requirement for an acute oral study (OPPTS 870.1100; OECD 425) in the rat. COMPLIANCE:
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