What is lupus anticoagulant syndrome
Lupus Anticoagulant Testing
In addition, about 40% of patients with lupus develop autoantibodies against various phospholipids--some of which have anticoagulant activity (phospholipid-beta-2-glycoprotein I, for example); Antiphospholipid antibodies “inactivate” or “block” these normal anticoagulant effects leading to abnormal clotting (that is, their action ...
Ohio University
Note that the indication "Hypercoag State" (ICD-9-CM 289.81) may map to any of five ICD-10-CM indications (Activated protein C resistance, Antiphospholipid syndrome, Lupus anticoagulant syndrome, Other primary thrombophilia, or Prothrombin gene mutation), and so the list is slightly larger, allowing more specificity.
[DOC File]There are some rare causes of CVA's in young people
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Many patients have secondary antiphospholipid syndrome due to a well-defined autoimmune disease, such as systemic lupus erythematosus (Chapter 5). In contrast, those who exhibit only the manifestations of a hypercoagulable state without evidence of other autoimmune disorder are designated as having primary antiphospholipid syndrome.
[DOC File]Thrombosis
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Procoagulation states – inherited and acquired – Factor V laiden, Protein C+S deficiency, Activated protein C resitance, Hyperhomocystienamia, Antiphospholipid (lupus anticoagulant) syndrome. Paradoxical embolism – Patent foramen ovale, ASD. Anaerysms rupture resulting in haemorrhagic strokes. Vasculitis – including SLE.
[DOCX File]Cairo University
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Positive finding of antiphospholipid antibodies based on 1) abnl serum level of IgG or IgM anticardiolipin abs, 2) a positive test result for lupus anticoagulant using a standard method, or 3) a false-positive serological test for syphilis known to be positive for ≥ 6 months and confirmed by Treponema pallidum immobilization or fluorescent ...
[DOC File]RHEUMATOLOGY - Home | Stanford Medicine
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Risk factor, osteonecrosis, systemic lupus erythematosus, meta-analysis Introduction. Systemic lupus erythematosus (SLE) is a chronic systemic autoimmune disease with heterogeneous performance [1]. It can produce a variety of autoantibodies, with complement activation and immune complex deposition, resulting in damage to multiple tissues and ...
[DOC File]Anticoagulation Management Tool User Manual
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Systemic lupus erythematosus (SLE) is an autoimmune disease of chronic course characterized by the presence of autoantibodies to the cell nucleus. Antiphospholipid syndrome (APS) is considered the most common cause of acquired thrombophilias.
[DOC File]Risk factors for osteonecrosis in patients with systemic ...
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Management of antiphospholipid syndrome in SLE (SLE[Title] OR "lupus"[Title]) AND (anti-b2* OR anti-beta* OR anti-β2* OR anti-cardiolipin* OR anticardiolipin* OR "lupus anticoagulant" OR LAC OR aPL) AND (syndrome OR APS OR thrombosis OR thrombotic OR vascular OR pregnan* OR obstetric*) AND (management OR ...
Annals of the Rheumatic Diseases | A EULAR & BMJ ...
Antiphospholipid antibody syndrome (APA) The two most important APA are lupus anticoagulant (LA) and anticardiolipin(aCL).These antibodies may or may not be associated with clinical syndromes including arterial and venous thrombosis, thrombocytopaenia, obstetric complications such as recurrent spontaneous abortions and pre-eclampsia as well as ...
[DOC File]Keluarga IKMA FKMUA 2010 | Dunianya Mahasiswa IKM A …
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Assess anticoagulant medication adherence. Without guidance regarding alternative strategies to control heavy menses, women may self-decrease their warfarin dose to reduce menstrual flow. This can be life threatening. Assess potential for unintended pregnancy. Warfarin is a known teratogen and can cause birth defects when used by pregnant women.
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