Zosyn to oral antibiotic

    • [PDF File]Antibiotic Protocol for Empiric Therapy of Nosocomial ...

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      In many cases, the initial empiric antibiotic is not the best option for treatment of the patient’s infection. De-escalation is when we . switch to a narrower-spectrum antibiotic to target the causative pathogen(s) identified on culture. Key Point: The goal of de-escalation is to determine whether a narrower . antibiotic would be more appropriate


    • [PDF File]THE BEST ANTIBIOTIC SENSITIVITY CHART EVER (at least the ...

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      i. Antibiotic inactivation (beta lactamases) ii. Target site alteration by the bacteria (changes in PBPs and DNA gyrases) iii. Changes in the ability of the antibiotic to penetrate the cell wall of the bacteria b. Significant problems with Enterobacter, Klebsiella, Pseudomonas, Acineterbacter, Serratia, VRE, MRSA, TB IV. Combination Therapy a.


    • [PDF File]EMPIRIC ANTIBIOTIC GUIDELINES FOR SKIN AND …

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      Table of Contents Page 5 of 10 Esophageal Perforation Empiric Therapy Duration Infectious Diseases Consult strongly recommended 1st line: Piperacillin-tazobactam*4.5 g IV q6h + Fluconazole* 800 mg x1, then 400 mg q24h Low/medium-risk allergy2 to penicillins: Cefepime* 2 g IV q8h + Metronidazole 500 mg PO/IV q8h + Fluconazole* 800 mg x1, then 400 mg q24h


    • [PDF File]GUIDELINES FOR TREATMENT OF INTRA …

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      microbiologic history or antibiotic exposure), and the potential adverse effects of additional therapy. Clinicians should weigh the risk versu s benefit and consider addition of a second agent only in patients at particularly high risk for isolation of a resistant pathogen and those who are severely ill(e.g. septic shock).


    • [PDF File]ZOSYN (Piperacillin and Tazobactam for Injection, USP) Rx ...

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      o Use oral agents for simple and complicated cystitis o Pyelonephritis almost never requires vancomycin o Community-onset pyelonephritis: Ceftriaxone o Nosocomial Pyelonephritis or community disease with risk-factors for resistant pathogens: Cefepime, piperacillin-tazobactam, or …



    • Zosyn: Side Effects, Dosage & Uses

      Oral antimicrobials less potent than IV formulation. Step-down to a less potent oral agent requires individual patient assessment Parenteral Therapy Oral Therapy*** Oral Bioavailability Azithromycin 500 mg IV once daily x 3 days (5 days if suspected legionella) Azithromycin 500 mg PO x 1 then 250 mg PO once daily x 4 days Or


    • Intravenous to Oral (IV:PO) Anti-Infective Conversion Therapy

      48 hours of oral antibiotic therapy, consider adding or changing to an agent with anti-MRSA activity (i.e., TMP-SMX2 or doxycycline). Non-Purulent Cellulitis Absence of purulent drainage or exudate, ulceration, and no associated abscess. Includes erysipelas. Target Pathogens: Group A Streptococcus, Staphylococcus aureus (the role of community-


    • [PDF File]Intravenous to Oral Conversion for Antimicrobials

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      ZOSYN (piperacillin and tazobactam for injection, USP) is an injectable antibacterial combination product consisting of the semisynthetic antibiotic piperacillin sodium and the β­ lactamase inhibitor tazobactam sodium for intravenous administration. Piperacillin sodium is derived from D(-)-α-aminobenzyl-penicillin. The chemical name of


    • [PDF File]De-escalation

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      THE "BEST" ANTIBIOTIC SENSITIVITY CHART EVER (at least the best we could make) Created by James McCormack, BSc(Pharm), PharmD and Fawziah Lalji, BSc(Pharm), PharmD, FCSHP with assistance from Tim Lau Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC Gram Positive Cocci Anaerobes Streptococci Gram Negative Bacilli


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