Agonist vs antagonist drug

    • [DOCX File]WordPress.com

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      a. Drug B is a partial agonist acting at the same receptor as drug A. b. Drug A causes a greater maximal effect than drug B. c. When present in identical concentrations, drug A causes a greater effect than drug B. d. Drug A has a lower ED50 than drug B

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    • [DOCX File]www.lcps.org

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      Antagonist vs. agonist drugs. Inhibitory vs. excitatory neurotransmitter. The 7 psychological perspectives. Behavioral. ... Binocular vs. monocular cues for depth perception. Give examples of each type. ... Describe the following drugs/drug categories. cocaine-marijuana-heroine-alcohol-nicotine-LSD-An opiate-An amphetamine-

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    • [DOC File]Pharm Unit 2 - Shelbye's CSON Notes Blog

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      Agonist, partial agonist, antagonist. Partial agonist- partially mimics, if give with drug can compete with another drug and negate it or antagonize it--- produces low to moderate activation alone. Strong and moderate to strong. Table 28-1 Important Responses to Activation of Mu and Kappa Receptors. Opioid Agonists. STRONG: Morphine (Duramorph) CII

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    • [DOC File]Opioid Abuse and Dependence

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      3. Mixed agonist-antagonists: bind and activate one receptor type but not another. a. buprenorphine (Buprenex, Subutex): µ agonist and κ antagonist. b. Nalbuphine (Nubain): µ antagonist and κ agonist

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    • [DOC File]TOXICOLOGY – TEST 1 STUDY GUIDE

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      Agonist – This is when a drug binds to and activates a receptor site…drug was looking for that site. Antagonist – This is when a drug binds to a receptor and inhibits a biological response. This occurs either through competitive (reversible) or non-competitive (irreversible) actions. Efficacy – The degree to which a drug is able to ...

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    • [DOC File]Medicinal Chemistry (MDCH) 5220

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      What is an agonist, indirect agonist, competitive antagonist, non-competitive antagonist? Give an example of how binding a cell-surface receptor can lead to a cascade of biochemical reactions/interactions that amplifies the signal? For example, how can the binding of NE at a 1 adrenergic receptor cause the heart to increase its force and rate?

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    • [DOC File]PAIN MANAGEMENT – ANALGESICS

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      Avoid mixed agonist/antagonist in pts on full agonists-precipitate withdrawal. Do not use in patients with head injuries-depression. Chronic use during pregnancy may result in a dependent offspring. In pts with underlying respiratory dysfunction, respiratory failure can occur. Half-lives increased in patients with hepatic or renal dysfunction

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    • [DOCX File]Drug

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      dose titration technique - "rescue doses" (treat breakthrough pain while guiding dose escalation): in addition to regular doses around the clock or use of long-acting drugs, extra dose of drug with short half-life is offered q 2 h prn; rescue dose is based on standing dose (usually 5-10% of total daily dose); standing dose can be increased daily by total amount of rescue dose used if many ...

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    • [DOC File]Drug/Application - University of Arizona

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      Agonist actions at opioid receptor Less abuse potential than opioids Pentazocine (Talwin) Analgesic Weak antagonist effects at opioid receptor. Agonist actions at opioid receptor Respiratory depression at low dose BUT has ceiling effect i.e. not dose dependent. Low abuse potential. High doses – dysphoria and psychomimetic effects

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    • [DOC File]Pharmacology Study Guide – Test 2

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      Agonist binds to opioid pain receptor in brain & causes an analgesic response. Partial agonist: binds to pain receptor and causes only limited actions. Antagonist: reverses the efx of these on pain receptors. Primarily bind to mu, kappa & delta receptors. Many opiods have …

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    • [DOC File]1 - City Vision University

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      Agonist Antagonist Mark the Table labeled Psychoactive Drug/Neurotransmitter Relationships (ex: use a paper clip, or colored tag), it will be helpful for future reference. How Drugs Affect the Body. In 25 words or less, explain the concept of tolerance and how it relates to understanding addiction. Define the following types of tolerance ...

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    • [DOC File]Drug - University of Kentucky

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      5-HT4 agonist N&V (esp. w/ chemo) Extrapyramidal effects, restlessness, sedation, fatigue, nausea, diarrhea Promote gastric emptying (peripheral) & suppress vomiting (central) Prochlorperazine (Compazine) D2-receptor blocker (in CTZ) N&V Masks gag reflex, tranquilizer, jaundice Sulfasalizine (Azulfidine) 5-aminosalicylates

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    • [DOC File]Methylnaltrexone SQ NMEM FINAL 20091118

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      Methylnaltrexone bromide, a peripherally acting μ-opioid receptor antagonist, does not cross the blood-brain barrier, and thus has actions limited to peripheral tissues. The peripheral actions allow the quaternary amine to decrease peripheral opioid constipation side effects without reducing centrally acting opioid analgesic effects.

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    • [DOC File]1

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      agonist vs. antagonist chemicals – agonist is a chemical that mimics a naturally-occurring substance (neurotransmitter) in the body and produces the same physiological effect. Antagonist chemicals bind to a receptor and block it, producing no response and preventing other chemicals (drugs or receptor agonists) from binding or attaching to the ...

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